College of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, China.
Nanoscale. 2012 Sep 28;4(19):5954-9. doi: 10.1039/c2nr31809a. Epub 2012 Sep 4.
The design of fluorescent probes for turn-on sensing of anions has been especially significant because it can effectively enhance sensing sensitivity by decreasing the background interference. In the present work, we have systematically studied the potential applications of fluorescent quantum dots (QDs) in turn-on anion sensing. The fluorescence of QDs are firstly quenched by three different mechanisms, i.e. fluorescence resonance energy transfer, electron transfer and surface states modulated fluorescence. The fluorescence of the pre-quenched QDs can then be recovered by various anions due to the modulating effects of added anions on the interaction between QDs and QDs, the interaction between QDs and quenchers, and the surface chemistry of the quenched QDs, respectively. The results described here indicate that turn-on sensing of various anions by QDs-based systems can be achieved by rationally choosing fluorescence modulating strategies, demonstrating the versatility of QDs in the corresponding applications.
设计用于检测阴离子的荧光探针具有特别重要的意义，因为它可以通过降低背景干扰有效地提高检测灵敏度。在本工作中，我们系统地研究了荧光量子点（QD）在用于开启型阴离子检测中的潜在应用。QD 的荧光首先通过三种不同的机制被猝灭，即荧光共振能量转移、电子转移和表面态调制的荧光。由于添加的阴离子对 QD 与 QD 之间的相互作用、QD 与猝灭剂之间的相互作用以及猝灭 QD 的表面化学的调制作用，预猝灭的 QD 的荧光随后可以被各种阴离子恢复。这里描述的结果表明，通过合理选择荧光调制策略，可以实现基于 QD 的体系对各种阴离子的开启型检测，证明了 QD 在相应应用中的多功能性。
