Department of Neuroradiology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Neuroradiology. 2012 Dec;54(12):1293-301. doi: 10.1007/s00234-012-1075-z. Epub 2012 Sep 5.
A new era of stroke treatment may have begun with mechanical thrombectomy (MT) by fully deployed closed-cell self-expanding stents (stent-triever). Multiple case series and the first randomised controlled trials (RCTs) have now been published. More studies are under way involving large numbers of patients, which in turn has resulted in less strict "pragmatic" study protocols. Problems with current trials include a lack of standardisation in the conduct of the recanalisation procedure, the definition of primary endpoints such as the grade of arterial recanalisation and tissue reperfusion, and the post-surgical care provided. In Part 1 of this two part series, we outline the current situation and the major research questions.
随着机械血栓切除术（MT）的全展开闭孔自膨式支架（支架取栓器）的应用，卒中治疗可能已经进入了一个新纪元。现在已经发表了多项病例系列和首个随机对照试验（RCT）。更多的研究正在进行中，涉及大量患者，这反过来又导致了不太严格的“实用”研究方案。目前试验存在的问题包括再通手术操作缺乏标准化、主要终点（如动脉再通程度和组织再灌注）的定义以及术后护理等问题。在这篇两部分系列文章的第 1 部分中，我们概述了当前的情况和主要的研究问题。
