Kamal Naveed, Majmundar Neil, Damadora Nitesh, El-Ghanem Mohammad, Nuoman Rolla, Keller Irwin A, Schonfeld Steven, Rybinnik Igor, Gupta Gaurav, Roychowdry Sudipta, Al-Mufti Fawaz
a Department of Neurosurgery , Rutgers University, New Jersey Medical School , Newark , NJ , USA.
b Department of Neurology , Rutgers University, New Jersey Medical School , Newark , NJ , USA.
Br J Neurosurg. 2018 Jun;32(3):245-249. doi: 10.1080/02688697.2018.1426726. Epub 2018 Feb 8.
The purpose of this study is to review the history of treatments for acute ischemic stroke, examine developments in endovascular therapy, and discuss the future of the management of acute ischemic stroke.
A selective review of recent clinical trials for the treatment of acute ischemic stroke was conducted.
We reviewed completed trials of the management of acute ischemic stroke including intravenous thrombolytics, intraarterial thrombolytics, and thrombectomy. We also assessed the future direction of research by reviewing ongoing clinical trials.
The advancement of endovascular treatment for stroke has led to improved morbidity and mortality for patients. Future challenges include delivering these treatments to stroke centers worldwide.
本研究旨在回顾急性缺血性卒中的治疗历史，审视血管内治疗的进展，并探讨急性缺血性卒中管理的未来发展。
对近期治疗急性缺血性卒中的临床试验进行了选择性回顾。
我们回顾了已完成的急性缺血性卒中管理试验，包括静脉溶栓、动脉内溶栓和血栓切除术。我们还通过回顾正在进行的临床试验评估了未来的研究方向。
卒中血管内治疗的进展已降低了患者的发病率和死亡率。未来的挑战包括将这些治疗推广至全球的卒中中心。
