Transthyretin (TTR) cardiac amyloidosis.
作者信息
Ruberg Frederick L, Berk John L
机构信息
Amyloid Treatment and Research Program, Boston University School of Medicine and Boston Medical Center, Boston, MA 02118, USA.
出版信息
Circulation. 2012 Sep 4;126(10):1286-300. doi: 10.1161/CIRCULATIONAHA.111.078915.
Abstract
摘要
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Circulation. 2012 Sep 4;126(10):1286-300. doi: 10.1161/CIRCULATIONAHA.111.078915.
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Clinical features and survival in senile systemic amyloidosis: comparison to familial transthyretin cardiomyopathy.老年系统性淀粉样变的临床特征和生存：与家族性转甲状腺素蛋白心肌病的比较。
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本文引用的文献
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Prospective evaluation of the morbidity and mortality of wild-type and V122I mutant transthyretin amyloid cardiomyopathy: the Transthyretin Amyloidosis Cardiac Study (TRACS).前瞻性评估野生型和 V122I 突变转甲状腺素蛋白淀粉样心肌病的发病率和死亡率：转甲状腺素蛋白淀粉样变性心肌病研究（TRACS）。
Am Heart J. 2012 Aug;164(2):222-228.e1. doi: 10.1016/j.ahj.2012.04.015.
2
Why are some amyloidoses systemic? Does hepatic "chaperoning at a distance" prevent cardiac deposition in a transgenic model of human senile systemic (transthyretin) amyloidosis?为什么有些淀粉样变是全身性的？肝“远距离伴侣”是否可预防转甲状腺素蛋白（野生型）老年性系统性淀粉样变转基因模型中的心脏沉积？
FASEB J. 2012 Jun;26(6):2283-93. doi: 10.1096/fj.11-189571. Epub 2012 Feb 23.
3
Epigallocatechin-3-gallate as a potential therapeutic drug for TTR-related amyloidosis: "in vivo" evidence from FAP mice models.没食子儿茶素-3-没食子酸酯作为一种潜在的转甲状腺素相关淀粉样变性治疗药物的研究：来自家族性淀粉样多发性神经病变小鼠模型的“体内”证据。
PLoS One. 2012;7(1):e29933. doi: 10.1371/journal.pone.0029933. Epub 2012 Jan 10.
4
The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug.转甲状腺素淀粉样变性：从阐明与病理学相关的聚集分子机制到获得监管机构批准的药物。
J Mol Biol. 2012 Aug 10;421(2-3):185-203. doi: 10.1016/j.jmb.2011.12.060. Epub 2012 Jan 5.
5
Molecular imaging of amyloidosis: will the heart be the next target after the brain?淀粉样变性的分子影像学：继大脑之后，心脏会成为下一个目标吗？
Curr Cardiol Rep. 2012 Apr;14(2):226-33. doi: 10.1007/s11886-011-0239-5.
6
High-dose melphalan and peripheral blood stem cell transplantation for light-chain amyloidosis with cardiac involvement.高剂量马法兰和外周血干细胞移植治疗伴有心脏受累的轻链淀粉样变性。
Blood. 2012 Feb 2;119(5):1117-22. doi: 10.1182/blood-2011-07-370031. Epub 2011 Dec 6.
7
Familial amyloid polyneuropathy.家族性淀粉样多神经病。
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Proteomic typing of amyloid deposits in systemic amyloidoses.系统性淀粉样变性中淀粉样沉积物的蛋白质组学分型。
Amyloid. 2011 Dec;18(4):177-82. doi: 10.3109/13506129.2011.630762.
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Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis.强力霉素可减少转基因淀粉样变小鼠模型中的纤维形成。
Blood. 2011 Dec 15;118(25):6610-7. doi: 10.1182/blood-2011-04-351643. Epub 2011 Oct 12.
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