Hellekant C
Radiologe. 1979 Dec;19(12):521-7.
Selective bronchial angiography and short term intra-arterial infusions of Mitomycin C were performed in 70 patients with bronchogenic carcinoma. The courses were given 1--5 times with a median interval of 2 weeks. The angiograms were compared with chest radiograms and data obtained at bronchoscopy, mediastinoscopy, surgery or autopsy. The effect of therapy was evaluated with chest radiography and bronchoscopy. Among our first 36 patients an objective response was registered in 18/27 patients with squamous cell carcinoma, in 4/7 with adenocarcinoma and in 2/2 with small cell cancer. These results warrant further studies. Though not suitable as a routine procedure in the diagnostic work up of a patient with possible bronchogenic carcinoma bronchial angiogrpahy may contribute to a better staging when used e.g. in connection with intraarterial chemotherapy.
对70例支气管源性癌患者进行了选择性支气管血管造影和丝裂霉素C的短期动脉内灌注。疗程为1至5次,中位间隔时间为2周。将血管造影片与胸部X线片以及支气管镜检查、纵隔镜检查、手术或尸检所获得的数据进行比较。通过胸部X线摄影和支气管镜检查评估治疗效果。在我们最初的36例患者中,27例鳞状细胞癌患者中有18例、7例腺癌患者中有4例、2例小细胞癌患者中有2例出现了客观反应。这些结果值得进一步研究。虽然支气管血管造影不适合作为可能患有支气管源性癌患者诊断检查的常规程序,但例如在与动脉内化疗联合使用时,它可能有助于更好地进行分期。