Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 N. Zhongshan Road, Shanghai 200062, PR China.
Chemistry. 2012 Oct 8;18(41):12945-9. doi: 10.1002/chem.201202583. Epub 2012 Sep 5.
Rapid access: A base-mediated cycloaddition/oxidation reaction of hydrazines and electron-deficient 1,3-conjugated enynes gives pyrazole derivatives, some of which are not easily accessible by other methods (see scheme). The reaction conditions are mild, thus enabling a variety of functional groups to be tolerated.
一种基于碱基的环加成/氧化反应，可使腙和缺电子的 1,3-共轭烯炔生成吡唑衍生物，其中一些方法难以制备（见方案）。反应条件温和，因此可以容忍各种官能团。
