PI3K-PKB/Akt 通路。
PI3K-PKB/Akt pathway.
机构信息
Friedrich Miescher Institute for Biomedical Research, Basel 4058, Switzerland.
出版信息
Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a011189. doi: 10.1101/cshperspect.a011189.
Abstract
Protein kinase B (PKB, or Akt) plays a role in cell metabolism, growth, proliferation, and survival. Its activation is controlled by a multi-step process that involves phosphoinositide-3-kinase (PI3K).
摘要
蛋白激酶 B（PKB，也称为 Akt）在细胞代谢、生长、增殖和存活中发挥作用。其激活受多步过程控制，涉及磷酸肌醇-3-激酶（PI3K）。
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