Department of Ophthalmology, Hietzing Hospital, Wolkersbergenstrasse 1, Wien 1130, Austria.
Br J Ophthalmol. 2013 Jan;97(1):18-22. doi: 10.1136/bjophthalmol-2012-301899. Epub 2012 Sep 5.
To compare the intensity of posterior capsular opacification (PCO) between a 1-piece and a 3-piece microincision cataract surgery intraocular lens (MICS IOL) in a prospective randomised study.
80 eyes of 40 patients with age-related cataract were enrolled in this study. Each patient received a 1-piece MICS IOL (AF-1 NY-60, Hoya, Tokyo, Japan) in one eye and a 3-piece MICS IOL (AF-1 iMICS Y-60H, Tokyo, Hoya) in the other eye. At the 1-year follow-up, the patients were examined at the slit lamp, visual acuity was determined and standardised high-resolution digital retroillumination images were taken for objective quantification of regeneratory PCO using an automated image analysis software (AQUA).
The mean regeneratory PCO score (1-piece IOL: 0.2, 3-piece IOL 0.3, p=0.7) and the neodymium:yttrium-aluminium-garnet laser capsulotomy rate (two cases in 3-piece IOL group; p=0.5) were comparable low for both IOLs. Capsular folds occurred significantly more often in the 3-piece IOL group (p=0.02).
Modification of the MICS IOL from a 3-piece to a 1-piece haptic design caused in short term no significant change in PCO amount. Compared with the 3-piece IOL, the 1-piece IOL led to significantly less capsular folds 1 year after surgery.
在一项前瞻性随机研究中比较 1 件式和 3 件式微切口白内障手术人工晶状体（MICS IOL）的后囊混浊（PCO）强度。
本研究纳入了 40 例年龄相关性白内障患者的 80 只眼。每位患者的一只眼接受 1 件式 MICS IOL（AF-1 NY-60，Hoya，东京，日本），另一只眼接受 3 件式 MICS IOL（AF-1 iMICS Y-60H，东京，Hoya）。在 1 年随访时，在裂隙灯下检查患者，确定视力，并拍摄标准高分辨率数字后反射图像，使用自动图像分析软件（AQUA）对再生性 PCO 进行客观定量。
1 件式 IOL 的平均再生 PCO 评分（0.2）和 3 件式 IOL 的评分（0.3，p=0.7）以及钕：钇-铝-石榴石激光后囊切开术的发生率（3 件式 IOL 组 2 例；p=0.5）均较低。3 件式 IOL 组的囊袋皱褶发生率明显更高（p=0.02）。
MICS IOL 由 3 件式改为 1 件式设计，在短期内 PCO 量没有明显变化。与 3 件式 IOL 相比，1 件式 IOL 在手术后 1 年导致的囊袋皱褶明显更少。
