Hu Patrick P
International Cardiovascular Institute, 8275 S. Eastern Ave. Suite 200-385, Las Vegas, NV 89123, USA.
Clin Med Insights Cardiol. 2012;6:125-39. doi: 10.4137/CMC.S7540. Epub 2012 Aug 23.
Transcatheter aortic valve replacement (TAVR) was approved in the United States in late 2011, providing a critically needed alternative therapy for patients with severe aortic stenosis previously refused surgical aortic valve replacement (SAVR). Over 20,000 TAVR have been performed in patients worldwide since 2002 when Alain Cribier performed the first-in-man TAVR. This paper reviews the data from balloon expandable and self-expanding aortic stent valves as well as data comparing them with traditional surgical aortic valve replacement (SAVR). Complications using criteria established by the Valve Academic Research Consortium (VARC) are reviewed. Future challenges and possibilities are discussed and will make optimizing TAVR an important goal in the years to come.
经导管主动脉瓣置换术(TAVR)于2011年末在美国获得批准,为先前拒绝接受外科主动脉瓣置换术(SAVR)的严重主动脉瓣狭窄患者提供了急需的替代治疗方法。自2002年Alain Cribier实施首例人体TAVR以来,全球范围内已有超过20000例患者接受了TAVR。本文回顾了球囊扩张式和自膨胀式主动脉支架瓣膜的数据,以及将它们与传统外科主动脉瓣置换术(SAVR)进行比较的数据。使用瓣膜学术研究联盟(VARC)制定的标准对并发症进行了回顾。讨论了未来的挑战和可能性,这将使优化TAVR成为未来几年的一个重要目标。