School of Biomedical and Health Sciences, Victoria University, Werribee Campus, P.O. Box 14428, Melbourne, Vic 8001, Australia.
Food Chem. 2012 Dec 1;135(3):950-9. doi: 10.1016/j.foodchem.2012.05.058. Epub 2012 May 23.
Germination of seven selected commercially important grains was studied to establish its effects on the nutritional and chemical composition. The changes in the concentration of the nutrients, bioactive compounds and the inhibitory effect of extracts on α-glucosidase and α-amylase activities were investigated. These were measured through proximate analysis, inhibition assays and HPLC. Germinated sorghum and rye extracts inhibited (p<0.05) α-glucosidase activity, whereas barley and sorghum extracts exhibited higher inhibitory activities against α-amylase. Germinated grains contained substantial amounts of total phenolics with rye having significantly higher content compared with the non-germinated grains. Radical scavenging activities of the phenolic extracts were between 13% and 73% for non-germinated and 14% and 53% for germinated. Inositol phosphate (InsP) 4, 5 and 6 were noted in all the grains, but InsP 6 was significantly lower in concentration. This study indicates the potential of germinated barley, sorghum and rye for the development of effective physiologically bioactive compounds for the reduction of the risk of diabetic agents and colon cancer.
研究了七种商业上重要的谷物的发芽情况，以确定其对营养和化学成分的影响。研究了营养物质、生物活性化合物的浓度变化以及提取物对α-葡萄糖苷酶和α-淀粉酶活性的抑制作用。这些通过常规分析、抑制试验和 HPLC 进行测量。发芽的高粱和黑麦提取物抑制（p<0.05）α-葡萄糖苷酶活性，而大麦和高粱提取物对α-淀粉酶表现出更高的抑制活性。发芽的谷物含有大量的总酚类物质，其中黑麦的含量明显高于未发芽的谷物。酚类提取物的自由基清除活性在未发芽和发芽谷物中分别为 13%至 73%和 14%至 53%。所有谷物中都检测到肌醇六磷酸（InsP）4、5 和 6，但 InsP 6 的浓度明显较低。这项研究表明，发芽的大麦、高粱和黑麦具有开发有效生理生物活性化合物的潜力，可降低糖尿病和结肠癌的风险。
