Center of Food Biotechnology and Bioseparations, BIOREN, and ‡Technology and Processes Unit, CGNA, Universidad de La Frontera , Casilla 54-D, Temuco, Chile.
J Agric Food Chem. 2011 Mar 9;59(5):1630-7. doi: 10.1021/jf103461k. Epub 2011 Feb 4.
The objective of this work was to evaluate the antioxidant and antihemolytic activities of crude, aqueous, and organic-aqueous extracts of maqui ( Aristotelia chilensis ) and murta ( Ugni molinae Turcz.), together with their inhibiting effect on enzymes involved in the metabolism of carbohydrates. Radical scavenging activity, inhibition of linoleic acid oxidation in a micellar system, antihemolytic activity, and inhibition of α-amylases and α-glucosidases were analyzed. Crude extracts of maqui leaves and fruits were found to be important sources of polyphenolic compounds, showing 69.0 ± 0.9 and 45.7 ± 1.1 mg GAE/g dm, respectively. Polyphenols from maqui leaves were active as antioxidants and antihemolytic compounds (p < 0.05), showing a noncompetitive inhibiting effect on α-glucosidase. Flavan-3-ol polymers and glycosylated flavonols, such as quercetin glucoside and kaempferol glucoside, were tentatively identified in extracts. This preliminary observation provides the basis for further examination of the suitability of polyphenol-enriched extracts from maqui and murta as nutritional or medicinal supplements with potential human health benefits.
本研究旨在评估智利酒果（ Aristotelia chilensis ）和智利蔓越莓（ Ugni molinae Turcz.）的粗提物、水提物和有机溶剂-水提物的抗氧化和抗溶血活性，以及它们对参与碳水化合物代谢的酶的抑制作用。分析了自由基清除活性、胶束体系中亚油酸氧化抑制、抗溶血活性以及α-淀粉酶和α-葡萄糖苷酶抑制。智利酒果叶和果实的粗提取物被发现是多酚化合物的重要来源，分别显示出 69.0 ± 0.9 和 45.7 ± 1.1 mg GAE/g dm。智利酒果叶中的多酚具有抗氧化和抗溶血活性（p < 0.05），对α-葡萄糖苷酶表现出非竞争性抑制作用。在提取物中初步鉴定出黄烷-3-醇聚合物和糖苷化类黄酮，如槲皮苷和山柰酚糖苷。这一初步观察结果为进一步研究智利酒果和智利蔓越莓多酚富集提取物作为具有潜在人类健康益处的营养或药用补充剂的适宜性提供了依据。
