Department of Clinical Neuroscience, San Raffaele Scientific Institute, Milan, Italy.
Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10;40:26-9. doi: 10.1016/j.pnpbp.2012.08.007. Epub 2012 Aug 27.
This study examined baseline startle magnitude, using eye blink response and skin conductance response in anorexia nervosa patients. Twenty female in-patients with anorexia nervosa and an equal number of female healthy controls were tested. Baseline startle response was assessed during blank screens while four startling loud sounds (a 116 dB, 1s, 250 Hz tone) were delivered with a time interval ranging from 35 to 55 s. It was investigated if BMI and state anxiety correlated with physiological responses. The clinical sample showed a lower baseline startle reflex measured with both indices, than healthy controls. Across the whole sample, a single regression model partially explained the relationship between BMI and baseline skin conductance response.
本研究通过眨眼反应和皮肤电传导反应检测了神经性厌食症患者的基础惊跳幅度。共测试了 20 名神经性厌食症女性住院患者和 20 名健康女性对照。在空白屏幕期间评估基础惊跳反应，同时以 35 到 55 秒的时间间隔发出四个响亮的惊声（116dB，1s，250Hz 音）。研究了 BMI 和状态焦虑是否与生理反应相关。临床样本的两项指标测量的基础惊跳反射均低于健康对照组。在整个样本中，单一回归模型部分解释了 BMI 和基础皮肤电传导反应之间的关系。
