Reichel Valeska A, Schneider Nora, Grünewald Barbara, Kienast Thorsten, Pfeiffer Ernst, Lehmkuhl Ulrike, Korte Alexander
Department of Child and Adolescent Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Germany; Department of Psychiatry and Psychotherapy, Universitätsklinikum Halle (Saale), Halle, Germany.
Psychophysiology. 2014 Feb;51(2):168-77. doi: 10.1111/psyp.12160. Epub 2013 Nov 11.
In this study, we investigated the emotional processing of extremely emaciated body cues in adolescents and young adults with (n = 36) and without (n = 36) anorexia nervosa (AN), introducing a new picture type, which was taken from websites that promote extreme thinness and is targeted specifically at adolescents interested in extreme thinness. A startle reflex paradigm was used for implicit reactions, while a self-assessment instrument was used for subjective responses. We found a significant group difference with a startle inhibition (appetitive response) among the patients and a startle potentiation (aversive response) among the controls, whereas no such difference for subjective measures was found. The results are in contrast to previous studies, which proposed a general failure to activate the appetitive motivational system in AN, but in keeping with findings from other addictions, where the same response pattern has been found. Implications for prevention and therapy are discussed.
在本研究中,我们调查了患有(n = 36)和未患有(n = 36)神经性厌食症(AN)的青少年和青年成人对极度消瘦身体线索的情绪加工,引入了一种新的图片类型,该图片取自宣扬极度消瘦且专门针对对极度消瘦感兴趣的青少年的网站。采用惊吓反射范式来测量内隐反应,同时使用自我评估工具来测量主观反应。我们发现,患者组存在惊吓抑制(积极反应),而对照组存在惊吓增强(厌恶反应),两组之间存在显著差异,而主观测量未发现此类差异。这些结果与之前的研究相反,之前的研究认为神经性厌食症患者普遍无法激活积极动机系统,但与其他成瘾研究的结果一致,在其他成瘾研究中也发现了相同的反应模式。本文还讨论了这些结果对预防和治疗的启示。