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Multidiscip Respir Med. 2011 Apr 30;6(2):82-6. doi: 10.1186/2049-6958-6-2-82.
2
Factors associated with mortality in patients with exacerbation of chronic obstructive pulmonary disease hospitalized in General Medicine departments.与综合医学科住院的慢性阻塞性肺疾病加重患者死亡率相关的因素。
Intern Emerg Med. 2011 Feb;6(1):47-54. doi: 10.1007/s11739-010-0465-7. Epub 2010 Oct 1.
3
Chronic obstructive pulmonary disease: role of bacteria and updated guide to antibacterial selection in the older patient.慢性阻塞性肺疾病：细菌的作用以及老年患者抗菌药物选择的最新指南。
Drugs Aging. 2009;26(12):985-95. doi: 10.2165/11315700-000000000-00000.
4
Identification of exacerbations in obstructive lung disease through biomarkers.通过生物标志物识别阻塞性肺疾病加重。
Biomarkers. 2009 Nov;14(7):523-8. doi: 10.3109/13547500903150763.
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Dietary habits of firstly admitted Spanish COPD patients.初诊西班牙 COPD 患者的饮食习惯。
Respir Med. 2009 Dec;103(12):1904-10. doi: 10.1016/j.rmed.2009.06.001. Epub 2009 Jun 28.
6
Change in inflammation in out-patient COPD patients from stable phase to a subsequent exacerbation.门诊 COPD 患者从稳定期到随后加重期炎症变化。
Int J Chron Obstruct Pulmon Dis. 2009;4:101-9. doi: 10.2147/copd.s4854. Epub 2009 Apr 15.
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[Systemic markers of exacerbated chronic obstructive pulmonary disease: how they can help with the decision of whether or not to prescribe antibiotics].[慢性阻塞性肺疾病急性加重的全身标志物：它们如何有助于决定是否使用抗生素]
Arch Bronconeumol. 2008 Nov;44(11):581-3.
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Where is the supporting evidence for treating mild to moderate chronic obstructive pulmonary disease exacerbations with antibiotics? A systematic review.使用抗生素治疗轻至中度慢性阻塞性肺疾病加重期的支持证据在哪里？一项系统评价。
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[Antimicrobial treatment of exacerbation in chronic obstructive pulmonary disease: 2007 consensus statement].[慢性阻塞性肺疾病急性加重期的抗菌治疗：2007年共识声明]
Arch Bronconeumol. 2008 Feb;44(2):100-8. doi: 10.1016/s1579-2129(08)60013-0.
10
Can spirometry, pulse oximetry and dyspnea scoring reflect respiratory failure in patients with chronic obstructive pulmonary disease exacerbation?肺量计、脉搏血氧饱和度测定法和呼吸困难评分能否反映慢性阻塞性肺疾病急性加重患者的呼吸衰竭情况？
Med Princ Pract. 2007;16(5):378-83. doi: 10.1159/000104812.

因慢性阻塞性肺疾病急性加重而到急诊科就诊的患者中与住院相关的因素。

Factors associated with hospital admission in patients reaching the emergency department with COPD exacerbation.

作者信息

García-Sanz Maria Teresa, Pol-Balado Carlos, Abellás Concepción, Cánive-Gómez Juan Carlos, Antón-Sanmartin Diana, González-Barcala Francisco J

机构信息

Emergency Department, Salnés County Hospital, Ande-Rubiáns s/n, Vilagarcía de Arousa, Pontevedra, Spain.

出版信息

Multidiscip Respir Med. 2012 Jun 19;7(1):6. doi: 10.1186/2049-6958-7-6.

DOI:10.1186/2049-6958-7-6
PMID:22958396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3436640/
Abstract

BACKGROUND

The aim of this study was to determine the frequency of COPD exacerbations in our Emergency Department, as well as the hospitalization-related factors.

METHODS

Prospective observational study conducted in the Emergency Department of Salnés County Hospital among patients admitted for COPD exacerbation. Admission predictors were determined by multivariate analysis.

RESULTS

There were 409 exacerbations in 239 patients (79% male, mean age 75). 57% of exacerbations required hospitalization. Hospitalization-related factors were impaired oxygenation (p < 0.001), presence of neutrophilia (p < 0.01) and prescription of antibiotics in the Emergency Department (p < 0.05).

CONCLUSIONS

COPD exacerbation accounts for over 1% of all visits to our Emergency Department. 57% of them required hospitalization. Impaired oxygenation, greater neutrophilia and prescription of antibiotics in the Emergency Department were associated with greater probability of admission.

摘要

背景

本研究的目的是确定我院急诊科慢性阻塞性肺疾病（COPD）加重的发生率以及与住院相关的因素。

方法

在萨尔内斯县医院急诊科对因COPD加重而入院的患者进行前瞻性观察研究。通过多变量分析确定入院预测因素。

结果

239例患者共出现409次病情加重（男性占79%，平均年龄75岁）。57%的病情加重需要住院治疗。与住院相关的因素包括氧合受损（p<0.001）、存在中性粒细胞增多（p<0.01）以及在急诊科使用抗生素（p<0.05）。

结论

COPD加重占我院急诊科所有就诊病例的1%以上。其中57%需要住院治疗。氧合受损、中性粒细胞增多程度较高以及在急诊科使用抗生素与入院可能性较大相关。