Belgian Cancer Registry, Rue Royale 215, B-1210 Brussels, Belgium.
Arch Public Health. 2011 Oct 24;69(1):2. doi: 10.1186/0778-7367-69-2.
In Belgium, breast cancer mortality has been monitored since 1954, whereas cancer incidence data have only been made available for a few years. In this article we update historical trends of breast cancer mortality and describe the recent breast cancer incidence.
Incidence data were extracted from the Belgium Cancer Registry from 2004 to 2006 for the Walloon and Brussels Regions and Belgium, and from 1999 to 2006 for the Flemish Region. The Directorate-general Statistics and Economic information provided the mortality data for the years 1954-1999 and 2004. The regional authorities of the Flemish and Brussels Regions provided the mortality data for the years 2000-2003 and 2005-2006.
In 2004, the World age-standardised breast cancer incidence for the whole of Belgium was 110 per 100, 000 person-years for all ages; and 172, 390 and 345 per 100, 000 person-years for the 35-49, 50-69, and 70+ age groups, respectively. The incidence rate was slightly higher in each age group in the Brussels Region. In Flanders, where the incidence could be observed during a longer period, an increase was observed until 2003 in the 50-69 age group, followed by a decrease. To the contrary, in the oldest age group, incidence continued to rise over the whole period, whereas no change in incidence was observed between 1999 and 2006 in the 35-49 age group.Mortality increased until the late 1980s and afterwards decreased in all regions and in age groups younger than 70. In women of 70 years and older, the decline began later.
The burden of breast cancer in Belgium is very high. In 2004, Belgium ranked first for the age-standardised incidence rate in Europe for all ages combined and in the 35-49 and 50-69 age groups. The impact of the known risk factors and of mammographic screening should be further studied. The mortality rate in Belgium ranked lower than incidence, suggesting favourable survival. Plausible explanations for the discrepancy between incidence and mortality are discussed.
在比利时，自 1954 年以来一直监测乳腺癌死亡率，而癌症发病率数据仅在近几年才公布。本文更新了乳腺癌死亡率的历史趋势，并描述了最近的乳腺癌发病情况。
发病率数据从 2004 年至 2006 年从瓦隆大区和布鲁塞尔大区以及比利时的比利时癌症登记处提取，从 1999 年至 2006 年从佛兰德斯大区提取。统计和经济信息总局提供了 1954 年至 1999 年和 2004 年的死亡率数据。佛兰德斯和布鲁塞尔大区的地区当局提供了 2000 年至 2003 年和 2005 年至 2006 年的死亡率数据。
2004 年，比利时全年龄段的乳腺癌发病率为每 10 万人年 110 例；35-49 岁、50-69 岁和 70 岁以上年龄组分别为 172、390 和 345 例。布鲁塞尔大区各年龄组的发病率略高。在佛兰德斯，发病率可以在较长时间内观察到，在 50-69 岁年龄组，发病率在 2003 年之前一直上升，之后下降。相反，在最年长的年龄组，发病率在整个时期继续上升，而在 35-49 岁年龄组，1999 年至 2006 年期间发病率没有变化。死亡率在 80 年代末之前一直在上升，之后在所有地区和 70 岁以下年龄组都有所下降。70 岁以上的妇女，下降开始得较晚。
比利时乳腺癌负担很重。2004 年，比利时在所有年龄组和 35-49 岁和 50-69 岁年龄组的年龄标准化发病率方面在欧洲排名第一。应进一步研究已知危险因素和乳房 X 线筛查的影响。比利时的死亡率低于发病率，表明生存率良好。对发病率和死亡率之间差异的合理解释进行了讨论。
