Barış Serap A, Yıldız Füsun, Başyiğit Ilknur, Boyacı Haşim, Ilgazlı Ahmet
Department of Pulmonary Disease, M, Kazım Dinç Kandıra Government Hospital, Kandıra, Kocaeli, Turkey.
Multidiscip Respir Med. 2011 Apr 30;6(2):92-6. doi: 10.1186/2049-6958-6-2-92.
To evaluate smoking and COPD prevalence amongst teachers working in the schools of Kocaeli City, Turkey.
In this cross-sectional study, a questionnaire focusing on respiratory symptoms and smoking habits was administered to all participants who accepted to join the study.All subjects also underwent a physical examination and a pulmonary function test performed with portable spirometer. According to GOLD criteria, subjects who had post-bronchodilator FEV1/FVC < 70% and negative reversibility test were classified as COPD.
A total of 685 teachers were included [female n = 307 (45%), male n = 378 (55%)] with mean age 38.9 ± 8.9 years. Smoking habit was evaluated in 660 subjects: 291 (44.1%) were smokers, 252 (38.2%) were non-smokers and 117 (17.7%) were ex-smokers. Pulmonary function test was available in 651 subjects and 510 (78.3%) were defined as normal on spirometric analysis. Small airway obstruction was found in 115 of the cases (17.7%) in whom FEF25-75 level was found to be lower than 70% predicted. FEV1/FVC level was lower than 70% in 16 subjects (2.5%). Five subjects who had positive reversibility test were excluded from the study. The remaining 11 subjects who were considered as COPD consisted of 2 (18%) females and 9 (82%) males. Six of these subjects were aged over 40 years.
Spirometry has an important role in early diagnosis of COPD. Spirometric evaluation of cases with risk factors for COPD could be helpful in diagnosing patients before the progressive decline in lung function begins. Further studies are needed to evaluate whether the interventional strategies at this stage such as smoking cessation could prevent the progression of disease.
评估土耳其科贾埃利市学校教师的吸烟率和慢性阻塞性肺疾病(COPD)患病率。
在这项横断面研究中,对所有同意参与研究的参与者发放了一份聚焦于呼吸道症状和吸烟习惯的问卷。所有受试者还接受了体格检查以及使用便携式肺活量计进行的肺功能测试。根据全球慢性阻塞性肺疾病倡议(GOLD)标准,支气管扩张剂后第一秒用力呼气容积(FEV1)/用力肺活量(FVC)<70%且可逆性测试为阴性的受试者被归类为慢性阻塞性肺疾病。
共纳入685名教师[女性n = 307(45%),男性n = 378(55%)],平均年龄38.9±8.9岁。对660名受试者的吸烟习惯进行了评估:291名(44.1%)为吸烟者,252名(38.2%)为非吸烟者,117名(17.7%)为既往吸烟者。651名受试者进行了肺功能测试,其中510名(78.3%)在肺活量分析中被定义为正常。115例(17.7%)受试者的用力呼气流量25%-75%(FEF25-75)水平低于预测值的70%,发现存在小气道阻塞。16名受试者(2.5%)的FEV1/FVC水平低于70%。5名可逆性测试呈阳性的受试者被排除在研究之外。其余11名被视为慢性阻塞性肺疾病的受试者包括2名(18%)女性和9名(82%)男性。这些受试者中有6名年龄超过40岁。
肺活量测定在慢性阻塞性肺疾病的早期诊断中具有重要作用。对有慢性阻塞性肺疾病危险因素的病例进行肺活量测定评估,可能有助于在肺功能开始进行性下降之前诊断患者。需要进一步研究来评估在这个阶段诸如戒烟等干预策略是否可以预防疾病进展。