Al Ghobain Mohammed, Al-Hajjaj Mohamed S, Wali Siraj Omar
Department of Medicine, Pulmonary Section, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Ann Saudi Med. 2011 Mar-Apr;31(2):129-33. doi: 10.4103/0256-4947.77485.
The prevalence of chronic obstructive pulmonary disease (COPD) in Saudi Arabia is unknown. The aim of this study was to estimate the prevalence of COPD among smokers more than 40 years of age attending primary healthcare clinics in Saudi Arabia.
A questionnaire was used in a cross-sectional collection of demographic data and other items related to diagnosis of COPD in patients visiting primary healthcare clinics.
Eligible subjects were current or ex-smokers and aged 40 years or above. Spirometry was performed according to American Thoracic Society criteria. Airflow obstruction was classified according to the 2003 update of the World Health Organization and Global Initiative for Chronic Obstructive Lung Disease criteria. COPD was defined as a ratio less than 0.70 of post-bronchodilator-predicted forced expiratory volume in the first second to forced vital capacity (FEV1/FVC <0.70).
Because of incomplete data or poor performance on spirometry, of 1380 subjects eligible for the study, only 501 subjects were eligible for data analysis. Seventy-one patients had an FEV1/FVC ratio <0.70, comprising 14.2% of the study population, of which 95.8% were males. Current smokers comprised 57 (80.3%) subjects. Of the 71 subjects who fulfilled the criteria for COPD diagnosis, none were found to be in COPD stage I; 40 (56.3%) were in stage II and 31 (43.6%) were in stage III of the disease.
Underdiagnosis of COPD in primary healthcare clinics in Saudi Arabia is common, but its extent is not different from the corresponding data available in the literature for other countries. Use of spirometry as a routine test for all patients older than 40 years of age and with a smoking history can help in early detection and proper diagnosis of COPD, which subsequently will help in implementation of preventive measures.
沙特阿拉伯慢性阻塞性肺疾病(COPD)的患病率尚不清楚。本研究旨在估计沙特阿拉伯40岁以上就诊于初级保健诊所的吸烟者中COPD的患病率。
采用问卷调查收集就诊于初级保健诊所患者的人口统计学数据及其他与COPD诊断相关的项目,为横断面研究。
符合条件的受试者为当前吸烟者或既往吸烟者,年龄40岁及以上。根据美国胸科学会标准进行肺功能测定。气流受限根据世界卫生组织和慢性阻塞性肺疾病全球倡议组织2003年更新的标准进行分类。COPD定义为支气管扩张剂后第一秒用力呼气容积与用力肺活量的比值小于0.70(FEV1/FVC<0.70)。
由于数据不完整或肺功能测定结果不佳,在1380名符合研究条件的受试者中,仅有501名受试者符合数据分析要求。71例患者的FEV1/FVC比值<0.70,占研究人群的14.2%,其中95.8%为男性。当前吸烟者有57名(80.3%)。在71名符合COPD诊断标准的受试者中,未发现处于COPDⅠ期的患者;40名(56.3%)处于Ⅱ期,31名(43.6%)处于Ⅲ期。
沙特阿拉伯初级保健诊所中COPD的漏诊情况较为常见,但其程度与其他国家文献中的相应数据并无差异。对所有40岁以上且有吸烟史的患者常规进行肺功能测定有助于COPD的早期发现和正确诊断,进而有助于实施预防措施。