Shimamura Y, Chikama M, Tanimoto T, Kawakami Y, Tsutsumi A
Department of Neurological Surgery, Kobe West Municipal Hospital, Japan.
J Neurosurg. 1990 Feb;72(2):285-8. doi: 10.3171/jns.1990.72.2.0285.
A 28-year-old woman with a left frontoparietal anaplastic astrocytoma was treated postoperatively with a combination of cisplatin and 1-(4-amino-2-methylpyrimidine-5-yl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU). The drugs were infused via the left supraophthalmic internal carotid artery in an attempt to avoid ocular toxicity. The patient subsequently developed blindness in the left eye and a right temporal hemianopsia from marked degeneration of the left optic nerve and tract. It is apparent that the placement of a catheter into the supraophthalmic carotid artery does not exclude visual complications.
一名28岁患有左额顶间变性星形细胞瘤的女性患者术后接受了顺铂和盐酸1-(4-氨基-2-甲基嘧啶-5-基)甲基-3-(2-氯乙基)-3-亚硝基脲（ACNU）联合治疗。为避免眼部毒性，药物经左眼动脉内侧颈动脉注入。患者随后因左视神经和视束明显变性而出现左眼失明和右颞侧偏盲。显然，将导管插入眼动脉内侧颈动脉并不能排除视觉并发症。
