布普品引起的口吃病例。
A case of bupropion-induced stuttering.
机构信息
Department of Clinical Sciences, The Commonwealth Medical College, Scranton, PA 17701, USA.
出版信息
Gen Hosp Psychiatry. 2013 Sep-Oct;35(5):574.e7-8. doi: 10.1016/j.genhosppsych.2012.07.003. Epub 2012 Sep 5.
OBJECTIVE
Stuttering is a frequent side effect of many psychotropic drugs, particularly antidepressants.
METHOD
This is a case report of a woman presenting with stuttering after starting bupropion treatment for her depression.
RESULTS
The patient's stuttering resolved after discontinuing the bupropion.
CONCLUSION
Neuroimaging and pharmacological studies have implicated dopamine in the pathophysiology of stuttering. Bupropion's ability to increase dopamine in the frontal cortex was suspected to have been involved in this patient's stuttering. However, further research is needed before causality can be assured.
目的
口吃是许多精神药物（尤其是抗抑郁药）的常见副作用。
方法
这是一例因抑郁而开始服用安非他酮后出现口吃的女性病例报告。
结果
患者停止使用安非他酮后口吃症状得到缓解。
结论
神经影像学和药理学研究表明，多巴胺在口吃的病理生理学中起作用。安非他酮增加前额叶皮质多巴胺的能力被怀疑与该患者的口吃有关。然而，在确定因果关系之前，还需要进一步的研究。
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