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重症监护病房再次探查后胸骨伤口感染的发生率和局部使用庆大霉素的情况。

Incidence of sternal wound infection after reexploration in the intensive care unit and the use of local gentamycin.

机构信息

Clinic for Cardiovascular Surgery, University Hospital of Zürich, Zürich, Switzerland.

出版信息

Ann Thorac Surg. 2012 Dec;94(6):2033-7. doi: 10.1016/j.athoracsur.2012.07.044. Epub 2012 Sep 7.

Abstract

BACKGROUND

Reoperation for bleeding is a known emergency complication after cardiac operations. When performed in the intensive care unit (ICU), sterility issues arise. Our aim was to examine the incidence of sternal wound infection (SWI) after reexploration in the ICU for bleeding with routine use of local gentamycin.

METHODS

From January 2003 until December 2009, 4,863 patients underwent cardiac operations through a median sternotomy at our institution. We conducted a retrospective database review identifying all patients who required reoperations. The occurrence of SWI in this group was compared with the general cardiac surgical population. Reoperations for bleeding during this period were conducted routinely in the ICU with prophylactic application of a gentamycin sponge between the sternal halves before closure in all cases.

RESULTS

Reexploration for bleeding was necessary in 302 patients (6.2%), and SWI occurred in 11, for a rate of 3.6%. SWI occurred in 174 of the 4,561 non-reexplored patients, for a similar rate of 3.8% (p>0.9). These values are similar to our overall rate of SWI of 3.8% (n=185) in the total cohort of 4,863 patients.

CONCLUSIONS

The incidence of SWI was not increased in our study group after emergency reoperation for bleeding in the ICU after the local use of gentamycin. Our data suggest that reexploration in an ICU setting for bleeding does not pose a sterility challenge and that life-threatening delays due to transfer to the operating theater may be avoided.

摘要

背景

心脏手术后出血再探查是一种已知的紧急并发症,在重症监护病房(ICU)进行时会出现无菌问题。我们的目的是研究在 ICU 因出血进行再探查时常规使用局部庆大霉素后胸骨伤口感染(SWI)的发生率。

方法

从 2003 年 1 月至 2009 年 12 月,我们机构的 4863 名患者通过正中胸骨切开术接受了心脏手术。我们进行了回顾性数据库审查,以确定所有需要再次手术的患者。将该组的 SWI 发生率与一般心脏手术人群进行比较。在此期间,所有患者均在 ICU 常规进行出血再探查,在所有病例中,在胸骨两半闭合前预防性应用庆大霉素海绵。

结果

302 名患者(6.2%)因出血需要再次探查,其中 11 名发生 SWI,发生率为 3.6%。在未进行探查的 4561 名患者中,有 174 名发生 SWI,发生率相似,为 3.8%(p>0.9)。这些值与我们在 4863 名患者的总队列中 SWI 的总体发生率 3.8%(n=185)相似。

结论

在 ICU 因出血进行紧急再探查后,局部使用庆大霉素并未增加我们研究组的 SWI 发生率。我们的数据表明,在 ICU 环境下因出血进行再探查不会带来无菌挑战,并且可以避免因转移到手术室而导致的危及生命的延迟。

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