Section of Palliative Medicine, Rigshospitalet, Copenhagen University Hospital, Denmark Multidisciplinary Pain Centre, Rigshospitalet, Copenhagen University Hospital, Denmark National Institute of Public Health, University of Southern Denmark, Denmark.
Pain. 2012 Dec;153(12):2332-2338. doi: 10.1016/j.pain.2012.07.023. Epub 2012 Sep 5.
Chronic pain is currently considered a public health problem with high costs to the individual and society. To improve prevention and treatment of chronic pain, epidemiologic studies are mandatory for assessing chronic pain. The aims of this study were to estimate the prevalence of chronic pain in the adult Danish population and to analyze associated factors such as diseases, immigration, and opioid use. This cross-sectional survey combines individual-based information from the Danish Health Survey (2010) and official Danish health and socioeconomic, individual-based registers. The simple random sample consisted of 25,000 individuals (≥16 years old) living in Denmark. In all, 60.7% completed a mailed or online questionnaire. Associations were examined with multiple logistic regression analysis. The study population consisted of 14,925 individuals in whom a high prevalence of chronic pain (26.8%, 95% confidence interval: 26.1 to 27.5) and a high prevalence of opioid consumption (4.5%) were observed. Other aspects of particular note: (1) a higher prevalence of chronic pain occurred among individuals with cardiovascular and chronic pulmonary diseases than among individuals with cancer; and (2) individuals with a non-Western background reported a higher pain prevalence, higher pain intensities, and more widespread pain than individuals with Danish background; however, opioids were more frequently used by native Danes. The prevalence of chronic pain as well as opioid use in Denmark are alarmingly high, and the relevance of opioid consumption is unknown.
慢性疼痛目前被认为是一个公共卫生问题，给个人和社会带来了高昂的成本。为了改善慢性疼痛的预防和治疗，流行病学研究对于评估慢性疼痛是必要的。本研究的目的是估计丹麦成年人群中慢性疼痛的患病率，并分析相关因素，如疾病、移民和阿片类药物的使用。这项横断面调查结合了丹麦健康调查（2010 年）和丹麦官方健康和社会经济、个体登记的个体基础信息。简单随机样本由 25000 名居住在丹麦的个体（≥16 岁）组成。共有 60.7%的人完成了邮寄或在线问卷调查。使用多因素逻辑回归分析检查了相关性。研究人群由 14925 名个体组成，其中慢性疼痛的高患病率（26.8%，95%置信区间：26.1-27.5）和阿片类药物高消费（4.5%）。其他值得注意的方面包括：（1）心血管和慢性肺部疾病患者的慢性疼痛患病率高于癌症患者；（2）与丹麦背景的个体相比，非西方背景的个体报告的疼痛患病率更高、疼痛强度更高、疼痛范围更广；然而，本土丹麦人更频繁地使用阿片类药物。丹麦慢性疼痛和阿片类药物使用的患病率高得令人震惊，阿片类药物消费的相关性尚不清楚。
