印度德里献血者中的人类免疫缺陷病毒感染情况。

Human immunodeficiency virus infection in the blood donors of Delhi, India.

作者信息

Singh Y N, Malaviya A N, Tripathy S P, Chaudhuri K, Khare S D, Nanu A, Bhasin R

机构信息

Department of Medicine, All India Institute of Medical Sciences, New Delhi.

出版信息

J Acquir Immune Defic Syndr (1988). 1990;3(2):152-4.

PMID:2295975

Abstract

In the present study, blood from paid and unpaid donors was screened for the presence of HIV infection using a competitive ELISA test. None of the 8,000 unpaid donors but 4 (0.23%) of the 1,700 paid donors showed evidence of HIV infection. All of these four ELISA-positive samples were confirmed by the Western blot test. The present study indicates that HIV infection has entered the group of paid donors in the Delhi metropolitan area. Careful donor screening, discouraging use of paid donors, and stringent screening of donated units of blood has become mandatory in India to prevent HIV transmission through blood and blood products.

摘要

在本研究中，使用竞争性酶联免疫吸附测定（ELISA）试验对有偿和无偿献血者的血液进行HIV感染筛查。8000名无偿献血者中无人检测出HIV感染迹象，但1700名有偿献血者中有4人（0.23%）检测出HIV感染迹象。所有这4个ELISA阳性样本均通过蛋白质印迹法检测得以确认。本研究表明，HIV感染已在德里大都市区的有偿献血者群体中出现。在印度，为防止HIV通过血液及血液制品传播，必须对献血者进行仔细筛查，不鼓励使用有偿献血者，并对所捐献的血液单位进行严格筛查。