Edwards D J, Hoy G, Saies A D, Hayes M G
From Sportsmed SA, Adelaide, Australia.
J Shoulder Elbow Surg. 1994 Jul;3(4):230-3. doi: 10.1016/S1058-2746(09)80040-2. Epub 2009 Feb 13.
Bioabsorbable implants have been advocated for use in repair of a torn glenoid labrum to correct shoulder instability. These implants have been thought to be safe and to have little toxicity, antigenicity, or adverse side effects. However, similar implants have been shown to cause nonspecific granulomatous reactions when implanted into bone or soft tissues in studies in both animals and human beings. This article reports the adverse effects of these implants in six shoulders of five patients who had repair of a damaged glenoid labrum. All patients reported increasing pain and loss of shoulder motion after insertion of these devices. All required a further arthroscopic lavage and debridement to reduce the inlracapsular synovitis. Granulomatous reactions were identified histologically in all cases. No long-term side effects were encountered, and all patients recovered satisfactorily.
生物可吸收植入物已被提倡用于修复撕裂的盂唇以纠正肩关节不稳。这些植入物被认为是安全的，几乎没有毒性、抗原性或不良副作用。然而，在动物和人类研究中，类似的植入物植入骨或软组织后已显示会引起非特异性肉芽肿反应。本文报告了这些植入物在5例修复受损盂唇的患者的6个肩部产生的不良反应。所有患者均报告在植入这些装置后疼痛加剧且肩关节活动丧失。所有人都需要进一步的关节镜灌洗和清创以减轻关节囊内滑膜炎。所有病例在组织学上均发现肉芽肿反应。未遇到长期副作用，所有患者均恢复良好。
