Department of Radiology, The University of Iowa , Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.
Br J Radiol. 2013 Jan;86(1021):18244135. doi: 10.1259/bjr/18244135. Epub 2012 Sep 6.
In three experiments, we studied the detection of multiple abnormality types using the satisfaction of search (SOS) paradigm, the provision of a computer-aided detection (CAD) of pulmonary nodules and a focused nodule detection task.
51 chest CT examinations (24 that demonstrated subtle pulmonary nodules and 27 that demonstrated no pulmonary nodules) were read by 15 radiology residents and fellows under two experimental conditions: (1) when there were no other abnormalities present except test abnormalities in the exams (non-SOS condition), and (2) when other abnormalities were present in the exams (SOS condition). Trials from the two conditions were intermixed. Readers were invited to return for two sessions: one in which the SOS condition was repeated with a simulated CAD; another in which only the non-SOS condition was presented. Detection accuracy was measured using receiver operating characteristic (ROC) analysis.
An SOS effect (reduced detection accuracy for the test nodules in the presence of the diverse added abnormalities) was not found. Average accuracy was much higher when the CAD prompt was provided, without cost in the detection of the added abnormalities. Accuracy for detecting nodules appearing without intermixed SOS trials was also substantially improved.
CT interpretation was highly task dependent. Nodule detection was poor in the general search task. Therefore, CAD may offer a greater performance improvement than demonstrated in experiments assessing CAD using focused search. The absence of SOS may be due to limited nodule detection even without other abnormalities. Advances in knowledge CAD prompts of nodules increase the detection accuracy of nodules and decrease the time to detection-without impairing the detection accuracy-of non-nodule abnormalities.
在三项实验中,我们使用满足搜索(SOS)范式、计算机辅助检测(CAD)肺结节和聚焦结节检测任务来研究对多种异常类型的检测。
对 51 例胸部 CT 检查(24 例显示有细微肺结节,27 例显示无肺结节)进行了 15 名放射科住院医师和研究员的阅读,他们处于两种实验条件下:(1)检查中除测试异常外没有其他异常(非 SOS 条件),(2)检查中存在其他异常(SOS 条件)。两种情况下的试验相互混合。邀请读者参加两个会话:一个是在 SOS 条件下重复使用模拟 CAD 的会话;另一个是仅呈现非 SOS 条件的会话。使用接收者操作特征(ROC)分析来测量检测准确性。
未发现 SOS 效应(在存在多种添加异常的情况下,测试结节的检测准确性降低)。当提供 CAD 提示时,平均准确性要高得多,并且添加的异常检测不会带来成本。在检测没有混合 SOS 试验的结节出现时,准确性也有了很大提高。
CT 解释高度依赖于任务。在一般搜索任务中,结节检测效果不佳。因此,CAD 可能比使用聚焦搜索评估 CAD 的实验中所示的性能提高更大。缺乏 SOS 可能是由于即使没有其他异常,结节检测也受到限制。CAD 提示结节的知识进步提高了结节的检测准确性,并缩短了检测时间,而不会降低对非结节异常的检测准确性。