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基于 SLM 光诱导图案化的全光微流控芯片,实现可重构介电泳捕获。

All-optical microfluidic chips for reconfigurable dielectrophoretic trapping through SLM light induced patterning.

机构信息

Istituto Nazionale di Ottica del CNR (CNR-INO), U.O.S. di Napoli, Via Campi Flegrei, 34 - 80078, Pozzuoli (NA), Italy.

出版信息

Lab Chip. 2012 Nov 7;12(21):4449-54. doi: 10.1039/c2lc40789b.

DOI:10.1039/c2lc40789b
PMID:22960732
Abstract

We explore a novel approach for fabricating polymeric microfluidic-channelled dielectrophoretic (DEP) chips by direct laser projection through a holographic Spatial-Light-Modulator (SLM) onto photorefractive crystal substrates. As the first step, an all-optical mould-free approach was used to fabricate the PDMS microfluidic channel, by exploiting the light induced space charge field in Fe-doped lithium niobate crystals, with the aim of integrating a microfluidic channel directly onto the functionalized substrate. Subsequently, as the second step, geometrical flexible DEP traps can be created onto the substrate by the same SLM holographic projection system. The experimental verification shows the trapping of flowing carbon nanotubes (CNTs) and the formation of chaining effects with graphite nanofibers. The main feature of the SLM is the ability to display an arbitrary light intensity pattern that is used here for fabricating the channels. Moreover, the reconfigurable trapping of CNTs is possible simply by the optical writing/erasing of various light intensity patterns projected by the SLM.

摘要

我们探索了一种通过直接激光投影到光折变晶体衬底上的全息空间光调制器(SLM)来制造聚合物微流控通道介电泳(DEP)芯片的新方法。作为第一步,通过利用掺铁铌酸锂晶体中的光致空间电荷场,采用全光学无模具方法制造 PDMS 微流道,目的是将微流道直接集成到功能化衬底上。随后,作为第二步,可以通过相同的 SLM 全息投影系统在衬底上创建几何灵活的 DEP 陷阱。实验验证了对流动碳纳米管(CNT)的捕获以及与石墨纳米纤维形成链状效应。SLM 的主要特点是能够显示任意光强图案,这里用于制造通道。此外,通过 SLM 投影的各种光强图案的光学写入/擦除,可以简单地实现 CNT 的可重构捕获。

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