Pediatrics Department, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Clin Rheumatol. 2012 Dec;31(12):1671-5. doi: 10.1007/s10067-012-2071-8. Epub 2012 Sep 9.
To examine the relationship between physical appearance concern and psychological distress in female adolescent patients with systemic lupus erythematosus (SLE) was the aim of this study. A total of 84 adolescent SLE female patients and 80 age-matching healthy adolescents were evaluated for levels of appearance concern and a range of illness-specific measures to determine how these demographic and clinical variables were related to the dependent variable psychological distress. The Systemic Lupus Erythematosus Disease Activity Index was used to assess disease activity. Assessment of depression was conducted through the children depression inventory (CDI). Appearance concern was measured using the Self-Perception Profile for Children. The total CDI was 18.5 ± 4.3, indicating that these patients had more depressive symptoms, comparing with age- and sex-matched healthy controls. Furthermore, a total of 32 (38.1 %) patients had CDI larger than 19 points, indicating that they have relatively higher risk in developing depression. The CDI in control group was significantly lower than that in the SLE group (11.4 ± 1.7 vs. 18.5 ± 4.3, t = 9.93, p < 0.05). Using correlation and multiple regression analyses, we found that both appearance concern and age were predictive of depression in patients with SLE, and the former was highly correlated. This indicates that appearance concern may be associated with depression in female adolescent SLE patients. The results suggest that appearance concern is strongly associated with depression in female adolescent patients with SLE and should be routinely assessed.
本研究旨在探讨系统性红斑狼疮（SLE）女性青少年患者的外貌关注与心理困扰之间的关系。共评估了 84 名青少年 SLE 女性患者和 80 名年龄匹配的健康青少年，评估外貌关注程度和一系列特定疾病的指标，以确定这些人口统计学和临床变量与因变量心理困扰之间的关系。采用系统性红斑狼疮疾病活动指数评估疾病活动度。通过儿童抑郁量表（CDI）评估抑郁情况。采用儿童自我知觉量表评估外貌关注。CDI 总分为 18.5±4.3，表明这些患者的抑郁症状较年龄和性别匹配的健康对照组更为严重。此外，共有 32 名（38.1%）患者的 CDI 大于 19 分，表明他们有相对更高的抑郁发病风险。对照组的 CDI 明显低于 SLE 组（11.4±1.7 比 18.5±4.3，t=9.93，p<0.05）。通过相关分析和多元回归分析，我们发现外貌关注和年龄均为 SLE 患者抑郁的预测因素，且前者与后者高度相关。这表明外貌关注可能与 SLE 女性青少年患者的抑郁有关。结果提示，外貌关注与 SLE 女性青少年患者的抑郁密切相关，应常规评估。
