Marchie T T, Oyobere O, Eze K C
Department of Radiology, University of Benin Teaching Hospital Benin - City, Nigeria.
Niger J Clin Pract. 2012 Jul-Sep;15(3):285-92. doi: 10.4103/1119-3077.100622.
The objective of this study was to determine the measurement of normal range of ultrasound (US) thyroid gland dimensions in school-aged children (6-16 years) in our environment and compared with what is obtained elsewhere.
A prospective ultrasound measurement study done in University of Benin Teaching Hospital Benin, Nigeria.
A prospective ultrasound (US) study of thyroid dimensions of 500 school-aged children in our environment consisting of 227 boys and 273 girls was done from 1 December 2006 to July 2007. The subjects were examined by the authors and subjects with palpable abnormal thyroid gland were excluded from the study. The thyroid dimensions (length, height, and diameter) were taken for each lobe by means of ultrasound (US). In addition volume of each thyroid lobe was calculated and the summation of volume of the lobes was taken as thyroid gland volume of each subject. Also height and weight of patients were documented from which the subject's body surface was calculated. Incidental thyroid gland lesion in US was excluded from the study. Using the Statistical program of social science (SPSS) and INSTAT (Graph Pad Inc. USA) the data were analyzed. Informed consent was obtained from all the subjects and the study was done in line with the ethical guidelines of the centers.
The US thyroid gland volume in school-aged children in Benin City from this study ranges between 1.17 cm 3 and 7.19 cm 3 , mean volume range of 1.76-4.95 cm 3 , median volume range of 1.73-4.73 cm 3 , and range of standard deviation from 0.39 cm 3 to 1.49 cm 3 . The average mean thyroid volume is 2.32 cm 3 with the following average dimensions; anteroposterior right lobe =1.06 cm, mediolateral right lobe = 1.01 cm and craniocaudal right lobe = 2.34 cm, and anteroposterior left lobe = 1.01 cm, mediolateral left lobe = 1.04 cm and craniocaudal left lobe = 2.41 cm for both boys and girls respectively. These data are significantly lower than data obtained by European based World Health Organization/International Council for the Control of Iodine Deficiency Disorders (WHO/ICCIDD) 1997. However there is significant similarity with data obtained in similar environment.
Ultrasound thyroid gland dimensions in school-aged children in our environment are reproducible and the data obtained are comparable to those obtained in other environment. The values may be better used in our environment as reference data for screening purposes.
本研究的目的是确定我们环境中6至16岁学龄儿童甲状腺超声（US）正常尺寸范围的测量值，并与其他地方获得的数据进行比较。
在尼日利亚贝宁大学教学医院进行的一项前瞻性超声测量研究。
2006年12月1日至2007年7月，对我们环境中500名学龄儿童的甲状腺尺寸进行了前瞻性超声（US）研究，其中包括227名男孩和273名女孩。作者对受试者进行了检查，甲状腺可触及异常的受试者被排除在研究之外。通过超声（US）测量每个叶的甲状腺尺寸（长度、高度和直径）。此外，计算每个甲状腺叶的体积，并将叶体积的总和作为每个受试者的甲状腺体积。还记录了患者的身高和体重，并据此计算受试者的体表面积。研究排除了超声检查中偶然发现的甲状腺病变。使用社会科学统计程序（SPSS）和INSTAT（美国Graph Pad公司）对数据进行分析。所有受试者均获得了知情同意，研究按照各中心的伦理准则进行。
本研究中贝宁市学龄儿童的超声甲状腺体积在1.17 cm³至7.19 cm³之间，平均体积范围为1.76 - 4.95 cm³，中位数体积范围为1.73 - 4.73 cm³，标准差范围为0.39 cm³至1.49 cm³。平均甲状腺体积为2.32 cm³，平均尺寸如下：男孩和女孩的右叶前后径均为1.06 cm，右叶中外径均为1.01 cm，右叶头尾径分别为2.34 cm和2.41 cm，左叶前后径均为1.01 cm，左叶中外径均为1.04 cm，左叶头尾径分别为2.34 cm和2.41 cm。这些数据显著低于基于欧洲的世界卫生组织/国际碘缺乏病控制理事会（WHO/ICCIDD）1997年获得的数据。然而，与在类似环境中获得的数据有显著相似性。
我们环境中学龄儿童的超声甲状腺尺寸具有可重复性，获得的数据与其他环境中获得的数据具有可比性。这些值在我们的环境中可能更适合用作筛查目的的参考数据。
