Müller-Leisse C, Tröger J, Khabirpour F, Pöckler C
Abteilung Pädiatrische Radiologie, Kinderklinik der Universität Heidelberg.
Dtsch Med Wochenschr. 1988 Dec 2;113(48):1872-5. doi: 10.1055/s-2008-1067904.
Thyroid gland volume was calculated from ultrasound data (using the ellipsoid formula) in 1080 apparently healthy schoolchildren, aged 7-20 years, from Speyer and Neckargemünd in the Federal Republic of Germany. Thyroid volume was found to increase with age: mean of 4.34 ml (single standard deviation [SD] 1.55) in seven-year olds, 13.6 ml (SD 6.2) in 16-year olds. No measurable increase was found from the 16th year onwards. No sex-related differences in size were found before the age of ten years, with a slight size increase in girls at the time of puberty. The right lobe was significantly larger than the left one (mean difference of 0.8 ml) in all age groups. There was a weakly positive correlation between thyroid volume and age, body weight, height and surface area, respectively, the best correlation for both sexes being between thyroid volume and body surface area. Among the 1080 children and juveniles of both ages there were eight with abnormal findings, all of them girls aged 16-18 years old.
对来自德意志联邦共和国施派尔市和内卡河畔格明德市的1080名7至20岁看似健康的学童，根据超声数据（使用椭圆体公式）计算甲状腺体积。发现甲状腺体积随年龄增加：7岁儿童平均为4.34毫升（单标准差[SD]1.55），16岁儿童为13.6毫升（SD 6.2）。从16岁起未发现可测量的增加。10岁之前未发现大小存在性别差异，青春期时女孩的甲状腺体积略有增加。在所有年龄组中，右叶明显大于左叶（平均差异为0.8毫升）。甲状腺体积分别与年龄、体重、身高和体表面积呈弱正相关，男女甲状腺体积与体表面积的相关性最佳。在这两个年龄段的1080名儿童和青少年中，有8人有异常发现，均为16至18岁的女孩。
