Mikołajczak Aleksandra, Borszewska-Kornacka Maria Katarzyna, Bokiniec Renata
Department of Neonatal and Intensive Neonatal Care, Medical University, Warsaw, Poland.
Am J Perinatol. 2015 Nov;32(13):1257-62. doi: 10.1055/s-0035-1552937. Epub 2015 May 29.
This study aims to establish the reference ranges for normal thyroid gland (length, width, depth, and volume) in healthy term Polish neonates within the first week of life to aid in the comparative evaluation of infants with suspected thyroid disease.
A total of 148 term neonates from mothers with normal thyroid function were examined during their first week of life. Ultrasound examination was performed in both longitudinal and transverse projections to create reference value percentile charts for thyroid volume in healthy term neonates.
Median (range) width, depth, and length were 0.714 (range, 0.470-0.959), 0.677 (range, 0.527-0.960), 2.07 (range, 1.540-2.870) cm for the right lobe of the thyroid: and 0.720 (range, 0.535-1.010), 0.678 (range, 0.521-0.952), 2.015 (range, 1.620-2.730) cm for the left. Volumes for right lobe, left lobe, and both lobes combined were 0.502 (range, 0.228-0.931), 0.511 (range, 0.294-0.959), and 1.014 (range, 0.526-1.849) mL.
Diagnostic ultrasound examination of the thyroid in the neonate is a simple and useful method for assessment of thyroid gland disease and neonatal health. This study provides robust normative data for Polish newborns. Furthermore, we have found different values compared with other countries, particularly Scotland, which underlines the importance of establishing population-based data.
本研究旨在确定健康足月波兰新生儿出生后第一周甲状腺（长度、宽度、深度和体积）的正常参考范围，以辅助对疑似甲状腺疾病的婴儿进行比较评估。
对148名甲状腺功能正常母亲所生的足月新生儿在其出生后第一周进行检查。通过纵向和横向超声检查，为健康足月新生儿创建甲状腺体积参考值百分位图。
甲状腺右叶的宽度、深度和长度的中位数（范围）分别为0.714（范围，0.470 - 0.959）、0.677（范围，0.527 - 0.960）、2.07（范围，1.540 - 2.870）厘米；左叶分别为0.720（范围，0.535 - 1.010）、0.678（范围，0.521 - 0.952）、2.015（范围，1.620 - 2.730）厘米。右叶、左叶及两叶总和的体积分别为0.502（范围，0.228 - 0.931）、0.511（范围，0.294 - 0.959）、1.014（范围，0.526 - 1.849）毫升。
新生儿甲状腺的诊断性超声检查是评估甲状腺疾病和新生儿健康的一种简单且有用的方法。本研究为波兰新生儿提供了可靠的规范数据。此外，我们发现与其他国家（特别是苏格兰）的值不同，这突出了建立基于人群数据的重要性。
