Department of Neurology, University of Washington, Harborview Medical Center, Seattle, Wahington 98104-2499, USA.
Semin Neurol. 2012 Apr;32(2):154-60. doi: 10.1055/s-0032-1322588. Epub 2012 Sep 8.
Myelopathy refers to a spinal cord disorder that presents with motor and/or sensory deficits. Infectious agents that cause myelopathy do so by either direct infection of neural structures (e.g., polio), a parainfectious mechanism (with a presumed autoimmune pathogenesis), or as a result of involvement of structures adjoining the spinal cord, which may cause a compressive myelopathy. This review of infectious causes of myelopathy focuses on pathogens that are most relevant to clinicians in North America.
脊髓病是指一种以运动和/或感觉功能障碍为特征的脊髓疾病。引起脊髓病的感染因子可通过直接感染神经结构(例如,脊髓灰质炎)、副感染机制(假定的自身免疫发病机制)或由于与脊髓相邻结构的受累而导致脊髓压迫性病变。本文对引起脊髓病的感染性病因进行综述,重点介绍了与北美临床医生最相关的病原体。