Lyons Jennifer L
Continuum (Minneap Minn). 2015 Feb;21(1 Spinal Cord Disorders):100-20. doi: 10.1212/01.CON.0000461087.56371.e8.
This article reviews the common infectious etiologies of spinal cord dysfunction that span the globe epidemiologically and vary pathophysiologically.
Many microorganisms have the ability to directly or indirectly result in spinal cord dysfunction. These agents may have the ability to infect the spinal cord itself, but frequently cause indirect damage by parainfectious or postinfectious immune-mediated destruction or external compression of the spinal cord.
Infectious myelopathies can pose diagnostic difficulty but are potentially reversible causes of spinal cord dysfunction. The often complex relationship among the infectious agent, the immune system, and the neuraxis can create a difficult management conundrum whereby immune modulation may be the preferred approach.
本文回顾了全球范围内脊髓功能障碍的常见感染病因，其在流行病学上具有广泛性，在病理生理学上存在差异。
许多微生物能够直接或间接导致脊髓功能障碍。这些病原体可能有能力感染脊髓本身，但常常通过感染后或感染后免疫介导的破坏或脊髓外部压迫而造成间接损害。
感染性脊髓病可能会带来诊断难题，但却是脊髓功能障碍潜在的可逆转病因。感染因子、免疫系统和神经轴之间常常复杂的关系可能会造成一个棘手的管理难题，免疫调节可能是首选的治疗方法。
