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接受择期消融手术的癌症患者的自体输血

Autologous transfusions for cancer patients undergoing elective ablative surgery.

作者信息

Lichtiger B, Huh Y O, Armintor M, Fischer H E

机构信息

Division of Laboratory Medicine, University of Texas M.D. Anderson Cancer Center, Houston 77030.

出版信息

J Surg Oncol. 1990 Jan;43(1):19-23. doi: 10.1002/jso.2930430106.

Abstract

Patients who have cancer are exposed to the adverse consequences of blood transfusions, such as transmissible diseases. This study presents an examination of a program of autologous blood deposit for cancer patients undergoing elective surgical procedures. Over a 3-year period, 235 patients deposited 388 units of autologous blood: 6 for head and neck tumor surgery, 8 for neurosurgical tumors, 8 for gastrointestinal and colorectal tumor surgery, 14 for adrenal tumor surgery, 16 for gynecologic tumor surgery, 23 for soft tissue and bone tumor surgery, 25 for mastectomies and reconstructive breast surgery, 42 for genitourinary tumor surgery, and 93 for bone marrow aspirations for autologous transplants. One hundred eighty-two patients (77.4%) used 278 units (71.6%) of their autologous blood units during the operations, 50/182 required additional homologous blood, and 53 did not require transfusions with autologous blood. Our study shows that a majority of these patients (132/182) underwent surgery using only autologous transfusions. Therefore, we believe that predeposited autologous blood is a viable alternative to homologous blood for cancer patients undergoing surgery.

摘要

患癌症的患者会面临输血带来的不良后果,比如传染病。本研究对一项针对接受择期外科手术的癌症患者的自体血储存计划进行了考察。在3年期间,235名患者储存了388单位的自体血:6单位用于头颈部肿瘤手术,8单位用于神经外科肿瘤手术,8单位用于胃肠和结直肠肿瘤手术,14单位用于肾上腺肿瘤手术,16单位用于妇科肿瘤手术,23单位用于软组织和骨肿瘤手术,25单位用于乳房切除术和乳房重建手术,42单位用于泌尿生殖系统肿瘤手术,93单位用于自体移植的骨髓穿刺。182名患者(77.4%)在手术期间使用了278单位(71.6%)的自体血,182名中有50名需要额外的同源血,53名不需要输自体血。我们的研究表明,这些患者中的大多数(132/182)仅使用自体输血进行了手术。因此,我们认为对于接受手术的癌症患者,预先储存的自体血是同源血的可行替代品。

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