Kwan T, Pintea M, Garcia Morino F, Preston R R, Li J, Caruso C, Berlyne S D, Berlyne G M
Department of Medicine, Brooklyn VA Medical Center, N.Y.
Nephron. 1990;54(1):21-5. doi: 10.1159/000185804.
Tissue fluid and plasma oncotic pressure levels were measured in an unselected group of 13 patients presenting with congestive heart failure. Patients had a mean serum albumin of 3.6 g/dl +/- (SD) 0.35; serum oncotic pressure was 22.23 +/- 1.8 mm Hg; tissue fluid (lower leg) oncotic pressure was 0.985 +/- 0.34 mm Hg. The oncotic pressure gradient between plasma and tissue fluid was 21.25 Hg +/- 1.7. This is about 10 mm Hg greater than delta pi in normal man. The high value in congestive heart failure is a mechanism to protect against the formation of edema. The possible mechanisms responsible for the formation of edema in congestive heart failure are discussed.
对一组未经挑选的13例充血性心力衰竭患者测量了组织液和血浆渗透压水平。患者血清白蛋白平均为3.6 g/dl±（标准差）0.35；血清渗透压为22.23±1.8 mmHg；组织液（小腿）渗透压为0.985±0.34 mmHg。血浆与组织液之间的渗透压梯度为21.25 mmHg±1.7。这比正常男性的Δπ大约高10 mmHg。充血性心力衰竭时的高值是防止水肿形成的一种机制。文中讨论了充血性心力衰竭中水肿形成的可能机制。
