Division of Medical Toxicology, Department of Emergency Medicine, University of Pittsburgh Medical Center, PUH South Tower, Suite M2935, Pittsburgh, PA 15213, USA.
Toxicon. 2012 Dec 1;60(7):1287-9. doi: 10.1016/j.toxicon.2012.08.007. Epub 2012 Aug 30.
Documented envenomations by the pygmy rattlesnake (Sistrurus miliarius barbouri) are rare. While there have been no documented fatalities, several older case reports describe significant morbidity. We describe the first known case of pygmy rattlesnake envenomation that was treated with Crotalidae Polyvalent Immune Fab Antivenom (CroFab®).
A 28-year-old man with no significant past medical history presented after being envenomated on the right hand by his friend's pet pygmy rattlesnake. He developed swelling and pain in his hand and forearm. He responded well to a ten vial loading dose and a 18 h maintenance protocol of CroFab and was discharged the following day without developing any hematological or electrolyte derangements.
This is the first documented use of CroFab for S. m. barbouri envenomation. The outcome of this case suggests that CroFab is a safe treatment modality in this setting.
记录到的侏儒响尾蛇（Sistrurus miliarius barbouri）中毒事件很少见。虽然没有记录到致命的病例，但有几个较旧的病例报告描述了严重的发病率。我们描述了首例已知的用 Crotalidae Polyvalent Immune Fab Antivenom（CroFab®）治疗的侏儒响尾蛇中毒病例。
一名 28 岁的男子，无重大既往病史，因被朋友的宠物侏儒响尾蛇咬伤右手而就诊。他的手和前臂出现肿胀和疼痛。他对十支装的负荷剂量和 18 小时的 CroFab 维持方案反应良好，并于次日出院，没有出现任何血液学或电解质紊乱。
这是首例记录到的用 CroFab 治疗 S. m. barbouri 中毒的病例。该病例的结果表明，在这种情况下，CroFab 是一种安全的治疗方法。
