University of New Mexico Health Sciences Center, Department of Emergency Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; New Mexico Poison Center, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Division of Pediatric Emergency Medicine, Department of Emergency Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Toxicon. 2020 Sep;184:55-56. doi: 10.1016/j.toxicon.2020.05.026. Epub 2020 Jun 4.
The use of Fab antivenom (Crotalidae Polyvalent Immune Fab (Ovine) (CroFab); Boston Scientific) against North American Crotalidae envenomation is associated with the development of late- (≥4 days post-envenomation), new-onset of hematological abnormalities. Although attempts have been made to identify predictive indicators during the acute phase of an envenomation, of patients who are not at-risk of late-, new-onset of hematological abnormalities, there has been at least one prior report of a patient who developed thrombocytopenia that was unpredicted by current indicators. We add three cases of unpredicted, late-, new-onset of hematological abnormalities in patients with Fab-treated rattlesnake bite.
使用 Fab 抗蛇毒血清（Crotalidae Polyvalent Immune Fab (Ovine) (CroFab)；波士顿科学公司）治疗北美响尾蛇咬伤与晚期（≥4 天）新出现血液学异常有关。尽管已经尝试在蛇伤的急性期识别预测指标，但仍有至少一份先前的报告表明，有患者出现了血小板减少症，这是当前指标无法预测的。我们增加了 3 例 Fab 治疗响尾蛇咬伤患者出现无法预测的晚期新发生血液学异常的病例。
