Nestec Ltd., Nestle Research Center, PO Box 44, 1000 Lausanne 26, Switzerland.
J Colloid Interface Sci. 2013 Jan 1;389(1):147-56. doi: 10.1016/j.jcis.2012.07.073. Epub 2012 Aug 8.
Monodisperse water-in-oil-in-water (WOW) double emulsions have been prepared using microfluidic glass devices designed and built primarily from off the shelf components. The systems were easy to assemble and use. They were capable of producing double emulsions with an outer droplet size from 100 to 40 μm. Depending on how the devices were operated, double emulsions containing either single or multiple water droplets could be produced. Pulsed-field gradient self-diffusion NMR experiments have been performed on the monodisperse water-in-oil-in-water double emulsions to obtain information on the inner water droplet diameter and the distribution of the water in the different phases of the double emulsion. This has been achieved by applying regularization methods to the self-diffusion data. Using these methods the stability of the double emulsions to osmotic pressure imbalance has been followed by observing the change in the size of the inner water droplets over time.
使用微流控玻璃器件制备了单分散油包水包油（WOW）双乳液，这些器件主要由现成组件设计和构建而成。这些系统易于组装和使用。它们能够产生具有 100 至 40 μm 外径的双乳液。根据设备的操作方式，可以生产出含有单个或多个水滴的双乳液。对单分散油包水包水双乳液进行了脉冲场梯度自扩散 NMR 实验，以通过自扩散数据应用正则化方法来获取有关内相水核直径和双乳液各相中水的分布的信息。通过这种方法，通过观察内水相粒径随时间的变化，可以跟踪双乳液对渗透压失衡的稳定性。
