UCLA Department of Psychology, 1285 Franz Hall, Los Angeles, CA 90095-1563, USA.
Brain Behav Immun. 2012 Nov;26(8):1220-3. doi: 10.1016/j.bbi.2012.08.009. Epub 2012 Aug 31.
The focus on fatigue for the 2012 Named Series in brain, behavior, and immunity reflects the growing wave of research examining immune underpinnings of fatigue in healthy and clinical populations. Fatigue is prevalent in the general population and in patients with a variety of medical conditions. However, the etiology of fatigue remains elusive. Psychoneuroimmunological approaches to fatigue have yielded important advances in our understanding of this complex symptom and are represented in the twelve articles included in the Named Series. These articles include animal and human models of fatigue and cross a variety of different medical conditions, including cancer, chronic fatigue syndrome, and diabetes. This review briefly summarizes the articles included in the series and highlights the themes that have emerged from this body of work.
2012 年脑、行为和免疫专题系列重点关注疲劳,这反映了研究免疫在健康人群和临床人群疲劳中作用的日益增长。疲劳在普通人群和患有各种疾病的患者中都很普遍。然而,疲劳的病因仍然难以捉摸。疲劳的心理神经免疫学方法在我们对这种复杂症状的理解方面取得了重要进展,这些进展体现在专题系列中的 12 篇文章中。这些文章包括疲劳的动物和人类模型,并涵盖了多种不同的医学病症,包括癌症、慢性疲劳综合征和糖尿病。本文简要总结了专题系列中的文章,并突出了这组研究工作中出现的主题。