Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, Brazil.
Spinal Cord. 2013 Mar;51(3):193-5. doi: 10.1038/sc.2012.104. Epub 2012 Sep 11.
Cross sectional study, including 38 outpatients. Standardized questionnaire was used and urine cultures were performed.
To study spinal cord-injured (SCI) patients bladder management, clinical aspects that symptomatic urinary tract infection (SUTI) may present and asymptomatic bacteriuria (AB) incidence with its antimicrobial susceptibility profile.
Spinal cord injury outpatient rehabilitation clinic.
Clean intermittent catheterization is used by 71% of the patients. SUTI may have atypical clinical presentation (shivers, spasticity increase, headaches). In total, 65.7% (N=25) of the patients presented AB. Among these, the microorganisms isolated were resistant mainly to Ampicillin, Sulfamethoxazole-Trimethoprim and Norfloxacin, whose resistance rates were, respectively 73.3%, 60% and 33.3%.
Special attention should be given to possible atypical symptoms for SUTI. Although a small amount of urine samples was analyzed, resistance rates against Ampicillin, Sulfamethoxazole-Trimethoprim, Ciprofloxacin and Nitrofurantoin appear to be higher among SCI patients compared to the general population, thus demonstrating the need for continuous monitoring of microorganisms susceptibility, in order to avoid therapeutic failure when dealing with this specific population.
横断面研究，纳入 38 名门诊患者。采用标准化问卷和尿培养进行研究。
研究脊髓损伤（SCI）患者的膀胱管理、有症状尿路感染（SUTI）可能出现的临床特征以及无症状菌尿（AB）的发生率及其抗菌药物敏感性谱。
脊髓损伤门诊康复诊所。
71%的患者采用间歇性清洁导尿。SUTI 可能表现为不典型的临床症状（寒战、痉挛增加、头痛）。共有 65.7%（N=25）的患者出现 AB。其中，分离出的微生物主要对氨苄西林、磺胺甲恶唑-甲氧苄啶和诺氟沙星耐药，其耐药率分别为 73.3%、60%和 33.3%。
应特别注意 SUTI 可能出现的不典型症状。尽管只分析了少量尿液样本，但与普通人群相比，SCI 患者对氨苄西林、磺胺甲恶唑-甲氧苄啶、环丙沙星和呋喃妥因的耐药率似乎更高，因此需要持续监测微生物的敏感性，以避免在治疗这一特定人群时出现治疗失败。
