Per Huseyin, Canpolat Mehmet, Sahin Ugur, Gumus Hakan, Konuskan Bahadir, Kumandas Sefer
Department of Pediatric Neurology, Erciyes University Medical Faculty, Kayseri, Turkey.
Saudi Med J. 2012 Sep;33(9):942-7.
To determine the role of serum and urine selenium, and boron levels in children with resistant epilepsy.
Serum and urine boron and selenium levels were studied in 53 cases (32 boys and 21 girls) diagnosed with resistant epilepsy between April 2006 and February 2007 at the Department of Pediatric Neurology, Erciyes University, Kayseri, Turkey. Differences between groups were assessed using Student's t-test. Countable data were defined as percentage. Inter-group difference was assessed by Chi-square test. P-values less than 0.05 were considered significant.
When serum and urine boron and selenium levels were evaluated and compare with controls, a statistically significant difference was found in serum selenium, urine selenium, and urine boron levels (p<0.05). No significant difference was found in serum boron levels (p>0.05).
It was observed that there is a need for selenium supplementation in treatment of patients with resistant epilepsy, while no etiologic role is observed for boron.
确定血清和尿液中硒及硼水平在难治性癫痫患儿中的作用。
于2006年4月至2007年2月在土耳其开塞利埃尔西耶斯大学儿科神经科，对53例（32名男孩和21名女孩）诊断为难治性癫痫的患儿的血清和尿液硼及硒水平进行了研究。采用学生t检验评估组间差异。可计数数据定义为百分比。采用卡方检验评估组间差异。P值小于0.05被认为具有统计学意义。
评估并比较血清和尿液硼及硒水平与对照组时，发现血清硒、尿液硒和尿液硼水平存在统计学显著差异（p<0.05）。血清硼水平未发现显著差异（p>0.05）。
观察到在难治性癫痫患者的治疗中需要补充硒，而未观察到硼有病因学作用。
