Weeth H J, Speth C F, Hanks D R
Am J Vet Res. 1981 Mar;42(3):474-7.
Yearling beef heifers were offered drinking water (0.8 mg of B/L of water) to which 0, 15, 30, 60, or 120 mg of B/L of water was added for 10-day periods. Feed and water consumption were unaffected by treatments. There were no overt signs of toxicosis. Increased B ingestion increased plasma and urine B concentrations. The percentage of renally filtered B that was excreted was increased with the 30, 60, and 120 mg of B/L of water treatments, and B clearance exceeded endogenous creatinine clearance with these treatments. Ingesting increased amounts of B was associated with decreased plasma PO4(-3) concentration and increased renal clearance and urinary excretion of PO4(-3). The B status of cattle can be predicted from plasma or urine B concentrations. Results indicated that prediction can be made from the B/creatinine ratio of urine. With an induced urine sample, the equation for predicting B ingestion is Y = -67.79 + 976.74X - 141.91X2 (r = 0.96; Syx = 121.57) where Y is B in milligrams per 100 kg of body weight per day, and X is the ratio of urine B (mg/L of urine) to creatinine (mg/L of urine).
给一岁龄肉用小母牛提供饮用水（每升水中含硼0.8毫克），分别添加0、15、30、60或120毫克硼/升，持续10天。饲料和水的消耗量不受处理的影响。没有明显的中毒迹象。硼摄入量增加会使血浆和尿液中的硼浓度升高。在每升水含30、60和120毫克硼的处理中，经肾脏滤过的硼排泄百分比增加，且这些处理下硼清除率超过内源性肌酐清除率。摄入更多量的硼与血浆中磷酸根（PO4(-3)）浓度降低以及磷酸根的肾脏清除率和尿排泄增加有关。牛的硼状态可通过血浆或尿液中的硼浓度来预测。结果表明，可根据尿液中硼与肌酐的比值进行预测。对于诱导尿液样本，预测硼摄入量的方程为Y = -67.79 + 976.74X - 141.91X2（r = 0.96；Syx = 121.57），其中Y是每天每100千克体重中的硼毫克数，X是尿液中硼（毫克/升尿液）与肌酐（毫克/升尿液）的比值。
