Departamento de Clínica Médica, Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, GO, Brasil.
J Bras Pneumol. 2012 Jul-Aug;38(4):445-51. doi: 10.1590/s1806-37132012000400006.
To compile fiberoptic bronchoscopy findings in patients diagnosed with lung cancer and to correlate those with histopathological findings.
This was a retrospective study involving 212 patients with a confirmed diagnosis of lung cancer by cytological evaluation of BAL specimens or by histopathological evaluation of endobronchial or transbronchial biopsy specimens. The data were collected at the Respiratory Endoscopy Sector of Hospital São Salvador, located in the city of Goiânia, Brazil, between 2005 and 2010. The endoscopic findings were classified as endoscopically visible tumor, endoscopically invisible tumor, mucosal injury, as well as being classified by the presence/type of secretion. The visible tumors were also classified according to their location in the tracheobronchial tree.
Endobronchial mass (64%) and mucosal infiltration (35%) were the main endoscopic findings. The histological type was determined in 199 cases, the most prevalent types being squamous carcinoma, in 78 (39%), adenocarcinoma, in 42 (21%) small cell carcinoma, in 24 (12%), and large cell carcinoma, in 2 (1%). More than 45% of the visible tumors were at the upper bronchi. Squamous carcinoma (n = 78) was most commonly visualized as an endobronchial mass (in 74%), mucosal infiltration (in 36%), luminal narrowing (in 10%), or external compression (in 6%).
Our results show that the endobronchial mass is the most common bronchoscopic finding that is suggestive of malignancy. Proportionally, mucosal infiltration is the most common finding in small cell carcinoma. In adenocarcinoma, luminal narrowing, external compression, mucosal injury, and endobronchial secretion prevail.
编译经支气管镜活检或经支气管镜刷检细胞学诊断为肺癌患者的纤维支气管镜检查结果,并与组织病理学检查结果进行相关性分析。
本研究为回顾性研究,共纳入 212 例经支气管肺泡灌洗标本细胞学评估或经支气管镜或经支气管活检组织学评估确诊为肺癌的患者。研究数据收集于巴西戈亚尼亚市圣萨尔瓦多医院呼吸内镜科,时间为 2005 年至 2010 年。内镜检查结果按可直视肿瘤、不可直视肿瘤、黏膜损伤以及分泌物存在/类型进行分类。可见肿瘤也按其在气管支气管树的位置进行分类。
支气管内肿块(64%)和黏膜浸润(35%)是主要的内镜检查结果。199 例患者的组织学类型得到确定,最常见的类型为鳞状细胞癌 78 例(39%)、腺癌 42 例(21%)、小细胞癌 24 例(12%)和大细胞癌 2 例(1%)。超过 45%的可见肿瘤位于上支气管。78 例鳞状细胞癌(n=78)最常表现为支气管内肿块(74%)、黏膜浸润(36%)、管腔狭窄(10%)或外压(6%)。
本研究结果表明,支气管内肿块是最常见的提示恶性肿瘤的支气管镜下表现。比例上,黏膜浸润是小细胞癌最常见的表现。在腺癌中,管腔狭窄、外压、黏膜损伤和支气管内分泌物占主导地位。