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机械通气危重症患者手动过度充气联合呼气胸廓压缩以减少 ICU 住院时间。

Manual hyperinflation combined with expiratory rib cage compression for reduction of length of ICU stay in critically ill patients on mechanical ventilation.

机构信息

Hospital das Clínicas de Botucatu, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil.

出版信息

J Bras Pneumol. 2012 Jul-Aug;38(4):477-86. doi: 10.1590/s1806-37132012000400010.

DOI:10.1590/s1806-37132012000400010
PMID:22964932
Abstract

OBJECTIVE

Although manual hyperinflation (MH) is widely used for pulmonary secretion clearance, there is no evidence to support its routine use in clinical practice. Our objective was to evaluate the effect that MH combined with expiratory rib cage compression (ERCC) has on the length of ICU stay and duration of mechanical ventilation (MV).

METHODS

This was a prospective randomized controlled clinical trial involving ICU patients on MV at a tertiary care teaching hospital between January of 2004 and January of 2005. Among the 49 patients who met the study criteria, 24 and 25 were randomly assigned to the respiratory physiotherapy (RP) and control groups, respectively. Of those same patients, 6 and 8, respectively, were later withdrawn from the study. During the 5-day observation period, the RP patients received MH combined with ERCC, whereas the control patients received standard nursing care.

RESULTS

The two groups were similar in terms of the baseline characteristics. The intervention had a positive effect on the duration of MV, as well as on the ICU discharge rate and Murray score. There were significant differences between the control and RP groups regarding the weaning success rate on days 2 (0.0% vs. 37.5%), 3 (0.0% vs. 37.5%), 4 (5.3% vs. 37.5%), and 5 (15.9% vs. 37.5%), as well as regarding the ICU discharge rate on days 3 (0% vs. 25%), 4 (0% vs. 31%), and 5 (0% vs. 31%). In the RP group, there was a significant improvement in the Murray score on day 5.

CONCLUSIONS

Our results show that the use of MH combined with ERCC for 5 days accelerated the weaning process and ICU discharge.

摘要

目的

虽然手动过度充气(MH)被广泛用于清除肺部分泌物,但没有证据支持其在临床实践中的常规使用。我们的目的是评估 MH 联合呼气胸廓压缩(ERCC)对 ICU 住院时间和机械通气(MV)持续时间的影响。

方法

这是一项在 2004 年 1 月至 2005 年 1 月期间在一家三级教学医院接受 MV 的 ICU 患者参与的前瞻性随机对照临床试验。在符合研究标准的 49 名患者中,24 名和 25 名患者分别被随机分配到呼吸物理治疗(RP)组和对照组。在这些相同的患者中,分别有 6 名和 8 名患者后来退出了研究。在 5 天的观察期内,RP 组接受 MH 联合 ERCC,而对照组接受标准护理。

结果

两组患者的基线特征相似。干预措施对 MV 的持续时间以及 ICU 出院率和 Murray 评分均有积极影响。在第 2 天(0.0%对 37.5%)、第 3 天(0.0%对 37.5%)、第 4 天(5.3%对 37.5%)和第 5 天(15.9%对 37.5%)的撤机成功率以及第 3 天(0%对 25%)、第 4 天(0%对 31%)和第 5 天(0%对 31%)的 ICU 出院率方面,对照组和 RP 组之间存在显著差异。在 RP 组中,Murray 评分在第 5 天显著改善。

结论

我们的结果表明,使用 MH 联合 ERCC 治疗 5 天可加速撤机过程和 ICU 出院。

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