套细胞淋巴瘤国际预后指数：在常规实践中是否有效？
The Mantle Cell Lymphoma International Prognostic Index: Does it work in routine practice?
作者信息
Lim S Y, Horsman J M, Hancock B W
机构信息
Academic Unit of Clinical Oncology, Weston Park Hospital, Sheffield S10 2SJ, UK.
出版信息
Oncol Lett. 2010 Jan;1(1):187-188. doi: 10.3892/ol_00000034. Epub 2010 Jan 1.
Abstract
The Mantle Cell Lymphoma International Prognostic Index (MIPI) combines four factors to differentiate low-, intermediate- and high-risk prognostic groups in advanced mantle cell lymphoma using data from patients treated in clinical trials. To evaluate its use in routine practice, we applied the simplified index retrospectively to 50 consecutive new patients attending our lymphoma service. In the log-rank and multiple comparison statistical tests there was favorable differentiation between survival curves, and particularly between the high- and low-risk groups. We concluded that the MIPI is of value in routine lymphoma practice.
摘要
套细胞淋巴瘤国际预后指数（MIPI）结合了四个因素，利用临床试验中患者的数据，将晚期套细胞淋巴瘤患者分为低、中、高风险预后组。为了评估其在常规临床中的应用，我们对连续50例到我们淋巴瘤门诊就诊的新患者进行了简化指数的回顾性应用。在对数秩和多重比较统计检验中，生存曲线之间存在良好的区分，特别是高风险组和低风险组之间。我们得出结论，MIPI在淋巴瘤常规临床实践中有价值。
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