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Prenylated proteins: the structure of the isoprenoid group.

作者信息

Rilling H C, Breunger E, Epstein W W, Crain P F

机构信息

Department of Biochemistry, University of Utah, Salt Lake City 84112.

出版信息

Science. 1990 Jan 19;247(4940):318-20. doi: 10.1126/science.2296720.

DOI:10.1126/science.2296720
PMID:2296720
Abstract

The mevalonate-derived portion of a prenylated protein from Chinese hamster ovary cells has been established as diterpenoid (C20). This group is linked to a carboxyl-terminal cysteine as a thioether. It was removed from the protein by hydrazinolysis followed by Raney nickel desulfurization, and the resulting hydrocarbon fraction was analyzed by gas chromatography-mass spectrometry.

摘要

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