Prenylated proteins: the structure of the isoprenoid group.
作者信息
Rilling H C, Breunger E, Epstein W W, Crain P F
机构信息
Department of Biochemistry, University of Utah, Salt Lake City 84112.
出版信息
Science. 1990 Jan 19;247(4940):318-20. doi: 10.1126/science.2296720.
PMID:2296720
Abstract
The mevalonate-derived portion of a prenylated protein from Chinese hamster ovary cells has been established as diterpenoid (C20). This group is linked to a carboxyl-terminal cysteine as a thioether. It was removed from the protein by hydrazinolysis followed by Raney nickel desulfurization, and the resulting hydrocarbon fraction was analyzed by gas chromatography-mass spectrometry.
摘要
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