Medical Diagnostic Laboratories, LLC, Hamilton, NJ 08690, USA.
J Low Genit Tract Dis. 2012 Oct;16(4):352-7. doi: 10.1097/LGT.0b013e31824b9be2.
The study aimed to compare the overall detection rate of Trichomonas vaginalis to Chlamydia trachomatis and Neiserria gonorrhea and report detection rates by age groups.
Real-time polymerase chain reaction was used to detect the presence of T. vaginalis, C. trachomatis, and N. gonorrhea in cervical samples obtained from patients during gynecological examinations. A total of 78,428, 119,451, and 117,494 samples from women age 12 to 75 years were retrospectively analyzed for the presence of T. vaginalis, C. trachomatis, and N. gonorrhea, respectively. T. vaginalis and C. trachomatis detection rates in Florida, New Jersey, and Texas were calculated in different age groups.
The overall detection rate was 4.3% for T. vaginalis, 3.8% for C. trachomatis, and 0.6% for N. gonorrhea. The overall detection rate of T. vaginalis in Florida was 4.7% (n = 22,504), in New Jersey was 3.6% (n = 22,249), and in Texas was 4.5% (n = 33,675). Calculation of infection rates with T. vaginalis revealed differences between selected age groups with the highest detection rates in all 3 states found in age group 46 to 55 years (6.2%), which was higher than the overall detection rates in other age groups (p < .05 for all states). For C. trachomatis, the highest detection rate was found in age group 12 to 25 years (7.3%).
The overall infection rates of T. vaginalis were higher compared with those of C. trachomatis and N. gonorrhea. Detection rates of T. vaginalis were found to be highest among women age 46 to 55 years and may be due to T. vaginalis infiltrating the subepithelial glands and being detected only during hormone-induced or antibiotic-induced changes in the vaginal flora.
本研究旨在比较阴道毛滴虫、沙眼衣原体和淋病奈瑟菌的总检出率，并按年龄组报告检出率。
采用实时聚合酶链反应检测妇科检查中宫颈标本中阴道毛滴虫、沙眼衣原体和淋病奈瑟菌的存在。回顾性分析了年龄在 12 至 75 岁的女性的 78428、119451 和 117494 例宫颈样本，以确定阴道毛滴虫、沙眼衣原体和淋病奈瑟菌的存在。计算了佛罗里达州、新泽西州和德克萨斯州不同年龄组阴道毛滴虫和沙眼衣原体的检出率。
阴道毛滴虫总检出率为 4.3%，沙眼衣原体为 3.8%，淋病奈瑟菌为 0.6%。佛罗里达州阴道毛滴虫总检出率为 4.7%（n=22504），新泽西州为 3.6%（n=22249），德克萨斯州为 4.5%（n=33675）。计算阴道毛滴虫感染率发现，各年龄组之间存在差异，所有 3 个州的最高检出率均出现在 46 至 55 岁年龄组（6.2%），高于其他年龄组的总检出率（所有州的 p<0.05）。对于沙眼衣原体，最高检出率出现在 12 至 25 岁年龄组（7.3%）。
与沙眼衣原体和淋病奈瑟菌相比，阴道毛滴虫的总感染率更高。阴道毛滴虫的检出率在 46 至 55 岁的女性中最高，这可能是由于阴道毛滴虫侵袭上皮下腺，并仅在阴道菌群因激素或抗生素诱导发生变化时被检测到。
