Behavioural Epidemiology Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Australia.
Prev Med. 2012 Dec;55(6):535-9. doi: 10.1016/j.ypmed.2012.08.024. Epub 2012 Sep 8.
Too much sitting is now understood to be a health risk that is additional to, and distinct from, too little exercise. There is a rapidly-accumulating evidence on relationships of prolonged sedentary time and patterns of sedentary time with cardio-metabolic risk biomarkers and health outcomes. There is, however, the need to gather dose-response evidence and develop a broader understanding of the set of mechanisms linking sedentary behavior to health outcomes. In addition to the further understanding of the associated health risks, there is a new health-behavior, and epidemiological and experimental research agenda to be pursued, which include measurement studies; understanding the relevant determinants-particularly environmental determinants of sedentary behavior; and, developing effective interventions. A broad-based body of evidence is needed to inform the research-translation agenda-identifying and developing the future public health initiatives, environmental and policy changes and clinical guidelines that may be required.
久坐现在被认为是一种健康风险，它与运动不足不同，而且是额外的风险。目前有大量证据表明，长时间久坐和久坐时间模式与心血管代谢风险生物标志物和健康结果之间存在关联。然而，需要收集剂量反应证据，并更全面地了解将久坐行为与健康结果联系起来的一系列机制。除了进一步了解相关健康风险外，还需要开展新的健康行为、流行病学和实验研究议程，包括测量研究；了解相关决定因素——特别是久坐行为的环境决定因素；并开发有效的干预措施。需要广泛的证据基础来为研究转化议程提供信息，确定和制定未来可能需要的公共卫生倡议、环境和政策变化以及临床指南。
