Diana Jake Christopher, Chauntry Aiden James, Cowley Emma, Paterson Craig, Struder Jeb F, Pagan-Lassalle Patricia, Meyer Michelle L, Lin Feng-Chang, Moore Justin B, Hanson Erik D, Stoner Lee
Department of Exercise and Sport Science, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Human Movement Science Curriculum, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
BMJ Open. 2024 Dec 27;14(12):e096116. doi: 10.1136/bmjopen-2024-096116.
Sedentary behaviour (SB) is detrimental to cardiometabolic disease (CMD) risk, which can begin in young adulthood. To devise effective SB-CMD interventions in young adults, it is important to understand which context-specific SB (CS-SB) are most detrimental for CMD risk, the lifestyle behaviours that cluster with CS-SBs and the socioecological predictors of CS-SB.
This longitudinal observational study will recruit 500 college-aged (18-24 years) individuals. Two laboratory visits will occur, spaced 12 months apart, where a novel composite CMD risk score (eg, arterial stiffness, metabolic and inflammatory biomarkers, heart rate variability and body fat distribution) will be calculated, and questionnaires to measure lifestyle behaviours and levels of the socioecological model will be administered. After each laboratory visit, total SB (activPAL) and CS-SB (television, transportation, academic/occupational, leisure computer, 'other'; ecological momentary assessment) will be measured across 7 days.
This study has received full ethical approval, and participants provide written informed consent. Our hypothesis is that certain CS-SB will show stronger associations with CMD risk, compared with total sedentary behaviour (T-SB), even after accounting for coexisting lifestyle behaviours. We also expect a range of intra-individual, inter-individual and physical environmental socioecological factors will predict CS-SB. Findings addressing both the primary and any secondary research aims will be submitted for publication in a high-impact peer-reviewed journal.
久坐行为(SB)对心血管代谢疾病(CMD)风险有害,这种风险在青年期就可能开始。为了设计针对青年的有效的SB-CMD干预措施,了解哪些特定环境下的久坐行为(CS-SB)对CMD风险危害最大、与CS-SB聚集的生活方式行为以及CS-SB的社会生态预测因素非常重要。
这项纵向观察性研究将招募500名大学年龄(18 - 24岁)的个体。将进行两次实验室访视,间隔12个月,期间将计算一个新的综合CMD风险评分(例如,动脉僵硬度、代谢和炎症生物标志物、心率变异性和体脂分布),并发放问卷以测量生活方式行为和社会生态模型水平。每次实验室访视后,将在7天内测量总的久坐行为(activPAL)和特定环境下的久坐行为(电视、交通、学术/职业、休闲电脑、“其他”;生态瞬时评估)。
本研究已获得全面伦理批准,参与者提供书面知情同意书。我们的假设是,即使在考虑共存的生活方式行为后,某些特定环境下的久坐行为与CMD风险的关联将比总的久坐行为(T-SB)更强。我们还预计一系列个体内、个体间和物理环境社会生态因素将预测特定环境下的久坐行为。针对主要和任何次要研究目标的研究结果将提交至高影响力的同行评审期刊发表。