Cornella J L, Bent A E, Ostergard D R, Horbach N S
Department of Obstetrics and Gynecology, University of California, Irvine.
Urology. 1990 Jan;35(1):96-7. doi: 10.1016/0090-4295(90)80025-i.
Ten patients with pure detrusor instability were treated in a prospective fashion with transdermal scopolamine. Seventy percent of patients experienced moderate to severe untoward symptoms requiring discontinuation of medication. Three of 10 patients (30%) demonstrated a subjective improvement although only 1 was able to tolerate the medication. No objective change in detrusor instability was demonstrated.
十名单纯逼尿肌不稳定患者接受了东莨菪碱透皮贴剂的前瞻性治疗。70%的患者出现中度至重度不良反应，需要停药。10名患者中有3名（30%）主观症状有所改善，但只有1名患者能够耐受该药物。逼尿肌不稳定未出现客观变化。
