Implant Dent. 2012 Oct;21(5):422-6. doi: 10.1097/ID.0b013e3182691873.
To evaluate the long-term survival rate of rough-surfaced implants placed in maxillary sinuses augmented with deproteinized bovine bone (Bio-Oss; Geistlich Pharma AG, Wolhusen, Switzerland).
Thirteen maxillary sinuses were augmented in 10 patients with Bio-Oss. After an average healing period of 13.8 months, 24 implants were placed. In 4 cases, biopsies were performed and submitted to histological analysis. Clinical and radiographic evaluation was performed 9 years after implant placement and minimum 8 years after functional loading.
At the 9-year control, all the 24 implants were still functional. Thus, the implant survival rate was 100%.
Bio-Oss is an acceptable substitute to the autogenous bone, and it can be used as a unique material for sinus floor elevation. Rough-surfaced implants placed in 100% Bio-Oss grafts showed a high survival rate (100%) on the long term. Larger clinical trials are necessary to confirm our results.
评估在使用脱蛋白牛骨（Bio-Oss；Geistlich Pharma AG，瑞士沃尔胡森）增强的上颌窦中植入粗糙表面种植体的长期存活率。
10 名患者的 13 个上颌窦采用 Bio-Oss 进行了增强。在平均 13.8 个月的愈合期后，植入了 24 个种植体。在 4 例情况下进行了活检，并进行了组织学分析。在种植体放置后 9 年和功能负载后至少 8 年进行了临床和影像学评估。
在 9 年的随访中，所有 24 个种植体仍然功能正常。因此，种植体存活率为 100%。
Bio-Oss 是自体骨的可接受替代品，可用作鼻窦底提升的独特材料。在 100% Bio-Oss 移植物中植入粗糙表面种植体的长期存活率（100%）较高。需要更大规模的临床试验来证实我们的结果。
