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1
Experimental documentation of the structural consequences of hydrogen-bonding interactions to the proximal cysteine of a cytochrome P450.
Angew Chem Int Ed Engl. 2012 Oct 8;51(41):10403-7. doi: 10.1002/anie.201205912. Epub 2012 Sep 11.
2
Exploring second coordination sphere effects in nitric oxide synthase.
J Biol Inorg Chem. 2016 Dec;21(8):997-1008. doi: 10.1007/s00775-016-1396-1. Epub 2016 Sep 29.
4
Is the ferric hydroperoxy species responsible for sulfur oxidation in cytochrome p450s?
Angew Chem Int Ed Engl. 2006 Dec 11;45(48):8221-3. doi: 10.1002/anie.200603411.
5
A thiolate-ligated nonheme oxoiron(IV) complex relevant to cytochrome P450.
Science. 2005 Nov 11;310(5750):1000-2. doi: 10.1126/science.1119092. Epub 2005 Oct 27.
7
Iron(IV)hydroxide pK(a) and the role of thiolate ligation in C-H bond activation by cytochrome P450.
Science. 2013 Nov 15;342(6160):825-9. doi: 10.1126/science.1244373.
8
The mystery of cytochrome P450 Compound I: a mini-review dedicated to Klaus Ruckpaul.
Biochim Biophys Acta. 2011 Jan;1814(1):46-57. doi: 10.1016/j.bbapap.2010.06.007. Epub 2010 Jun 15.

引用本文的文献

3
Enhanced Reactivities of Iron(IV)-Oxo Porphyrin Species in Oxidation Reactions Promoted by Intramolecular Hydrogen-Bonding.
Adv Sci (Weinh). 2024 May;11(19):e2310333. doi: 10.1002/advs.202310333. Epub 2024 Mar 13.
4
Revealing substrate-induced structural changes in active site of human CYP51 in the presence of its physiological substrates.
J Inorg Biochem. 2023 May;242:112167. doi: 10.1016/j.jinorgbio.2023.112167. Epub 2023 Feb 26.
5
Alternative modes of O activation in P450 and NOS enzymes are clarified by DFT modeling and resonance Raman spectroscopy.
J Inorg Biochem. 2020 Jun;207:111054. doi: 10.1016/j.jinorgbio.2020.111054. Epub 2020 Mar 13.
6
Electron Paramagnetic Resonance Spectroscopy as a Probe of Hydrogen Bonding in Heme-Thiolate Proteins.
Inorg Chem. 2019 Dec 2;58(23):16011-16027. doi: 10.1021/acs.inorgchem.9b02506. Epub 2019 Nov 15.
7
Structure of cytochrome P450 2B4 with an acetate ligand and an active site hydrogen bond network similar to oxyferrous P450cam.
J Inorg Biochem. 2018 Aug;185:17-25. doi: 10.1016/j.jinorgbio.2018.04.015. Epub 2018 Apr 30.
8
Active Site Structures of CYP11A1 in the Presence of Its Physiological Substrates and Alterations upon Binding of Adrenodoxin.
Biochemistry. 2017 Oct 31;56(43):5786-5797. doi: 10.1021/acs.biochem.7b00766. Epub 2017 Oct 20.
9
Spectroscopic studies of the cytochrome P450 reaction mechanisms.
Biochim Biophys Acta Proteins Proteom. 2018 Jan;1866(1):178-204. doi: 10.1016/j.bbapap.2017.06.021. Epub 2017 Jun 28.
10
Exploring second coordination sphere effects in nitric oxide synthase.
J Biol Inorg Chem. 2016 Dec;21(8):997-1008. doi: 10.1007/s00775-016-1396-1. Epub 2016 Sep 29.

本文引用的文献

1
A single-site mutation (F429H) converts the enzyme CYP 2B4 into a heme oxygenase: a QM/MM study.
J Am Chem Soc. 2012 Mar 7;134(9):4053-6. doi: 10.1021/ja211905e. Epub 2012 Feb 22.
6
Cytochrome P450 compound I: capture, characterization, and C-H bond activation kinetics.
Science. 2010 Nov 12;330(6006):933-7. doi: 10.1126/science.1193478.
8
P450 enzymes: their structure, reactivity, and selectivity-modeled by QM/MM calculations.
Chem Rev. 2010 Feb 10;110(2):949-1017. doi: 10.1021/cr900121s.
9
Characterization of the proximal ligand in the P420 form of inducible nitric oxide synthase.
J Am Chem Soc. 2009 Sep 2;131(34):12186-92. doi: 10.1021/ja901016a.

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